DNA Origami, The New Revolution To Come For Nanotechnology

For the past few decades, some scientists have known the shape of things to come in nanotechnology is tied to the molecule of life, DNA. This burgeoning field is called “DNA origami.” The moniker is borrowed from the art of conjuring up birds, flowers and other shapes by imaginatively folding a single sheet of paper. Similarly, DNA origami scientists are dreaming up a variety of shapes — at a scale one thousand times smaller than a human hair — that they hope will one day revolutionize computing, electronics and medicine. Now, a team of Arizona State University and Harvard scientists has invented a major new advance in DNA nanotechnology. Dubbed “single-stranded origami” (ssOrigami), their new strategy uses one long noodle-like strand of DNA, or its chemical cousin RNA, that can self-fold — without even a single knot — into the largest, most complex structures to date. And the strands forming these structures can be made inside living cells or using enzymes in a test tube, allowing scientists the potential to plug-and-play with new designs and functions for nanomedicine: picture tiny nanobots playing doctor and delivering drugs within cells at the site of injury.

A DNA origami with an emoji-like smiley face

I think this is an exciting breakthrough, and a great opportunity for synthetic biology as well,” said Hao Yan, a co-inventor of the technology, director of the ASU Biodesign Institute’s Center for Molecular Design and Biomimetics, and the Milton Glick Professor in the School of Molecular Sciences.

We are always inspired by nature’s designs to make information-carrying molecules that can self-fold into the nanoscale shapes we want to make,” he said.

As proof of concept, they’ve pushed the envelope to make 18 shapes, including emoji-like smiley faces, hearts and triangles, that significantly expand the design studio space and material scalability for so-called, “bottom-upnanotechnology.

Source: https://asunow.asu.edu/

The Smell Of Death

Scientists in Korea have developed a bioelectronicnose’ that can specifically detect a key compound produced in decaying substances. When food begins to rot, the smell that we find repulsive comes from a compound known as cadaverine. That is also the substance responsible for the stench of rotting bodies, or cadavers—hence the name. The compound is the result of a bacterial reaction involving lysine, which is an amino acid commonly found in various food products. A previous study has shown that a receptor in zebrafish has an affinity for cadaverine. To make this receptor in the laboratory, scientists have turned to Escherichia coli bacteria as a host cell because it can easily produce large quantities of proteins. However, the production of this receptor in E. coli has been a challenge because it needs to be embedded in a membrane.

In this study, a team of researchers led by Associate Professor Hong Seunghun at Seoul National University packaged the cadaverine receptor from the zebrafish into nanodiscs, which are water friendly, membrane-like structures. The researchers then placed the receptor-containing nanodiscs in a special orientation on a carbon nanotube transistor, completing the bioelectronic nose. During testing with purified test compounds and real-world salmon and beef samples, the nose was selective and sensitive for cadaverine, even at low levels. The researchers suggest that the detector could someday prove useful in natural disaster scenarios, to recover corpses for identification.

The findings have been published in the journal ACS Nano.

Source: http://pubs.acs.org/

Paraplegic Rats Walk After Stem Cell Treatment

Engineered tissue containing human stem cells has allowed paraplegic rats to walk independently and regain sensory perception. The implanted rats also show some degree of healing in their spinal cords. The research, published in Frontiers in Neuroscience, demonstrates the great potential of stem cellsundifferentiated cells that can develop into numerous different types of cells—to treat spinal cord injury.

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Spinal cord injuries often lead to paraplegia. Achieving substantial recovery following a complete tear, or transection, is an as-yet unmet challenge.

Led by Dr. Shulamit Levenberg, of the Technion-Israel Institute of Technology, the researchers implanted human stem cells into rats with a complete spinal cord transection. The stem cells, which were derived from the membrane lining of the mouth, were induced to differentiate into support cells that secrete factors for neural growth and survival.

The work involved more than simply inserting stem cells at various intervals along the spinal cord. The research team also built a three-dimensional scaffold that provided an environment in which the stem cells could attach, grow and differentiate into support cells. This engineered tissue was also seeded with human thrombin and fibrinogen, which served to stabilize and support neurons in the rat’s spinal cord.

Rats treated with the engineered tissue containing stem cells showed higher motor and sensory recovery compared to control rats. Three weeks after introduction of the stem cells, 42% of the implanted paraplegic rats showed a markedly improved ability to support weight on their hind limbs and walk. 75% of the treated rats also responded to gross stimuli to the hind limbs and tail.

In contrast, control paraplegic rats that did not receive showed no improved mobility or sensory responses.

In addition, the lesions in the spinal cords of the treated rats subsided to some extent. This indicates that their spinal cords were healing.

Source: https://medicalxpress.com/

Flying MotorBikes For Dubai Police

Dubai Police, already home to Lamborghini patrol cars and android officers, has decided to take to the skies in what can only be described as a flying motorbike.

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The vehicle, called the Scorpion and designed by Russian tech company Hoversurf, relies on four propellers to stay airborne, with the rider crouched precariously close to the exposed blades. Capable of 40 mph and a travel time of 25 minutes, the single-seat craft, which can carry 600 lbs, can also operate autonomously.

After appearing at tech shows earlier this year, Dubai Police has decided to add one to its list of cutting-edge gadgets, all part of the force’s “smart city” plans.

Unveiled at Dubai’s Gitex Technology show, the Scorpion was presented alongside a new electric motorbike concept by Japanese firm Mikasa — firmly rooted to the ground, but with a top speed of 124 mph according to the police and looking like something out of the film “Tron.”
Source: http://edition.cnn.com/

Lenses Provide Nano Scale X-ray Microscopy

Scientists at DESY (Germany) have developed novel lenses that enable X-ray microscopy with record resolution in the nanometre regime. Using new materials, the research team led by DESY scientist Saša Bajt from the Center for Free-Electron Laser Science (CFEL) has perfected the design of specialised X-ray optics and achieved a focus spot size with a diameter of less than ten nanometres. A nanometre is a millionths of a millimetre and is smaller than most virus particles. They successfully used their lenses to image samples of marine plankton.

Modern particle accelerators provide ultra-bright and high-quality X-ray beams. The short wavelength and the penetrating nature of X-rays are ideal for the microscopic investigation of complex materials. However, taking full advantage of these properties requires highly efficient and almost perfect optics in the X-ray regime. Despite extensive efforts worldwide this turned out to be more difficult than expected, and achieving an X-ray microscope that can resolve features smaller than 10 nm is still a big challenge.

 

The silica shell of the diatom Actinoptychus senarius, measuring only 0.1 mm across, is revealed in fine detail in this X-ray hologram recorded at 5000-fold magnification with the new lenses. The lenses focused an X-ray beam to a spot of approximately eight nanometres diameter – smaller than a single virus – which then expanded to illuminate the diatom and form the hologram

The new lenses consist of over 10 000 alternating layers of a new material combination, tungsten carbide and silicon carbide. “The selection of the right material pair was critical for the success,” emphasises Bajt. “It does not exclude other material combinations but it is definitely the best we know now.” The resolution of the new lenses is about five times better than achievable with typical state-of-the-art lenses.

We produced the world’s smallest X-ray focus using high efficiency lenses,” says Bajt. The new lenses have an efficiency of more than 80 per cent. This high efficiency is achieved with the layered structures that make up the lens and which act like an artificial crystal to diffract X-rays in a controlled way.

The researchers have reported their work in the journal Light: Science and Applications.

Source: http://www.desy.de/

Budweiser Orders 40 Tesla Electric Trucks

The list of companies placing orders for Tesla Semi electric trucks keeps growing weeks after the unveiling event last month. Now Anheuser-Busch, the brewer behind Budweiser, announced that it ordered 40 Tesla Semi trucks. Last week, DHL confirmed an order of 10 trucks – bringing the tally to just over 200 Tesla Semi trucks. The brewer says that it will include the electric trucks in its distribution network as part of its commitment to reduce its operational carbon footprint by 30 percent by 2025. Considering the size of their distribution network, they say that it would be the equivalent of removing nearly 500,000 cars from the road globally each year.

At Anheuser-Busch, we are constantly seeking new ways to make our supply chain more sustainable, efficient, and innovative. This investment in Tesla semi-trucks helps us achieve these goals while improving road safety and lowering our environmental impact,” commented James Sembrot, Senior Director of Logistics Strategy.

Tesla Semi is actually only one part of Anheuser-Busch’s effort to modernize its fleet. They also confirmed orders from Nikola Motors for their battery/fuel cell hydrogen trucks and Uber’s Otto autonomous trucks.

Last year, Uber’s Otto completed its first shipment by self-driving truck with an autonomous beer run with Budweiser.

Source: https://electrek.co/

3D-Printed Plastic Objects Connect To The Internet Without Any Electronics

Researchers from the University of Washington (UW) have developed 3D-printed plastic objects that can connect to the internet without any electronics or batteries. The researchers found a way to 3D-print plastic objects that can absorb or reflect ambient WiFi signals and send data wirelessly to any WiFi receiver like a smartphone or router.

Possible use cases include an attachment for laundry detergent that can sense when soap is running low, or a water sensor that notifies your smartphone when there is a leak.

As the UW explains in its news release, the researchers “replaced some functions normally performed by electrical components with mechanical motion activated by springs, gears, switches and other parts that can be 3-D printed — borrowing from principles that allow battery-free watches to keep time.” The scientists found that those mechanical motions can trigger gears and springs that connect to an antenna, all within the object.
The team opens new approach: “Can objects made of plastic materials be connected to smartphones and other Wi-Fi devices, without the need for batteries or electronics? A positive answer would enable a rich ecosystem of ‘talking objects3D printed with commodity plastic filaments that have the ability to sense and interact with their surroundings. Imagine plastic sliders or knobs that can enable rich physical interaction by dynamically sending information to a nearby Wi-Fi receiver to control music volume and lights in a room. This can also transform inventory management where for instance a plastic detergent bottle can self-monitor usage and re-order supplies via a nearby Wi-Fi device.
Such a capability democratizes the vision of ubiquitous connectivity by enabling designers to download and use our computational modules, without requiring the engineering expertise to integrate radio chips and other electronics in their physical creations. Further, as the commoditization of 3D printers continues, such a communication capability opens up the potential for individuals to print highly customized wireless sensors, widgets and objects that are tailored to their individual needs and connected to the Internet ecosystem
.”

Source: http://printedwifi.cs.washington.edu/
https://www.geekwire.com/

How To Remove Air Pollution Inside Cars

You might think sitting in your car with your windows closed keeps you safe from air pollution. The makers of a new pollution-busting filter say you’d be wrong.

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When you’re in your car you’re directly in the lanes of traffic and you’re actually taking air into the car. That’s coming from the exhaust of the cars in front of you. This means that there are greatly elevated levels of air pollution inside of a vehicle. This is both for nitrogen dioxide and for particulate matter“,  says Matthew Johnson,  Professor of Chemistry at the University of Copenhagen (Denmark).

Toxic air pollution passes through air inlets inside cars. Emissions from diesel vehicles are worst. The team from University of Copenhagen and start-up Airlabs has created Airbubbl, which contains two filters.
We have a chemical filter that’s removing nitrogen dioxide and ozone and odour from the air stream. We also have a high performance particle filter that’s removing soot and road dust and brake dust and these other components. We combine that inside this case. This plugs into the cigarette lighter. We have some quiet fans at the two ends of the device and we’ve used computational fluid dynamics in order to direct the airflow towards the passengers,” explains Johnson.
Independent tests in London saw nitrogen dioxide concentrations inside cars fall by 95 percent in 10 minutes. The Airbubbl is lightweight and easily attachable. A Kickstarter campaign has been launched to market the device.

Source: https://www.reuters.com/

Crowdfunding: https://www.kickstarter.com/

Swiss Army Knife NanoVaccine To Fight Tumors

Scientists are using their increasing knowledge of the complex interaction between cancer and the immune system to engineer increasingly potent anti-cancer vaccines.
Now researchers at the National Institute ofBiomedical Imaging and Bioengineering (NIBIB) have developed a synergistic nanovaccine packing DNA and RNA sequences that modulate the immune response, along with anti-tumor antigens, into one smallnanoparticle. The nanovaccine produced an immune response that specifically killed tumor tissue, while simultaneously inhibiting tumor-induced immune suppression. Together this blocked lung tumor growth in a mouse model of metastatic colon cancer.

Large particles (left) containing the DNA and RNA components are coated with electronically charged molecules that shrink the particle. The tumor-specific neoantigen is then complexed with the surface to complete construction of the nanovaccine.
Upper left: electron micrograph of large particle

 

The molecular dance between cancer and the immune system is a complex one and scientists continue to identify the specific molecular pathways that rev up or tamp down the immune system. Biomedical engineers are using this knowledge to create nanoparticles that can carry different molecular agents that target these pathways. The goal is to simultaneously stimulate the immune system to specifically attack the tumor while also inhibiting the suppression of the immune system, which often occurs in cancer patients. The aim is to press on the gas pedal of the immune system while also releasing the emergency brake.

A key hurdle is to design a system to reproducibly and efficiently create a nanoparticle loaded with multiple agents that synergize to mount an enhanced immune attack on the tumor. Engineers at the NIBIB report the development and testing of such a nanovaccine in the journal Nature Communications.

Source: https://www.nibib.nih.gov/

How To Trap DNA molecules With Your Smartphone

Researchers from the University of Minnesota College of Science and Engineering have found yet another remarkable use for the wonder material graphenetiny electronictweezers” that can grab biomolecules floating in water with incredible efficiency. This capability could lead to a revolutionary handheld disease diagnostic system that could be run on a smart phoneGraphene, a material made of a single layer of carbon atoms, was discovered more than a decade ago and has enthralled researchers with its range of amazing properties that have found uses in many new applications from microelectronics to solar cells. The graphene tweezers developed at the University of Minnesota are vastly more effective at trapping particles compared to other techniques used in the past due to the fact that graphene is a single atom thick, less than 1 billionth of a meter.

The physical principle of tweezing or trapping nanometer-scale objects, known as dielectrophoresis, has been known for a long time and is typically practiced by using a pair of metal electrodes. From the viewpoint of grabbing molecules, however, metal electrodes are very blunt. They simply lack the “sharpness” to pick up and control nanometer-scale objects.

Graphene is the thinnest material ever discovered, and it is this property that allows us to make these tweezers so efficient. No other material can come close,” said research team leader Sang-Hyun Oh, a Professor at the University of Minnesota. “To build efficient electronic tweezers to grab biomolecules, basically we need to create miniaturized lightning rods and concentrate huge amount of electrical flux on the sharp tip. The edges of graphene are the sharpest lightning rods.

The team also showed that the graphene tweezers could be used for a wide range of physical and biological applications by trapping semiconductor nanocrystals, nanodiamond particles, and even DNA molecules. Normally this type of trapping would require high voltages, restricting it to a laboratory environment, but graphene tweezers can trap small DNA molecules at around 1 Volt, meaning that this could work on portable devices such as mobile phones.

The research study has been published  in Nature Communications.

Source: https://cse.umn.edu/

Copycat Robot

Introducing T-HR3, third generation humanoid robot designed to explore how clever joints can improve brilliant balance and real remote controlToyota says its 29 joints allow it to copy the most complex of moves – safely bringing friendly, helpful robots one step closer.


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Humanoid robots are very popular among Japanese people…creating one like this has always been our dream and that’s why we pursued it,” says Akifumi Tamaoki, manager of Partner robot division at Toyota.

The robot is controlled by a remote operator sitting in an exoskeletonmirroring its master’s moves, a headset giving the operator a realtime robot point of view.

We’re primarily focused on making this robot a very family-oriented one, so that it can help people including services such as carer” explains Tamaoki.
Toyota said T-HR3 could help around the homes or medical facilities in Japan or construction sites, a humanoid helping hand – designed for a population ageing faster than anywhere else on earth.

Source: http://toyota.com/

Nanotechnology Boosts CyberSecurity Against Hackers

The next generation of electronic hardware security may be at hand as researchers at New York University Tandon School of Engineering  (NYU Tandon) introduce a new class of unclonable cybersecurity security primitives made of a low-cost nanomaterial with the highest possible level of structural randomness. Randomness is highly desirable for constructing the security primitives that encrypt and thereby secure computer hardware and data physically, rather than by programming.

In a paper published in the journal ACS Nano, Assistant Professor of Electrical and Computer Engineering Davood Shahrjerdi and his team at NYU Tandon offer the first proof of complete spatial randomness in atomically thin molybdenum disulfide (MoS2). The researchers grew the nanomaterial in layers, each roughly one million times thinner than a human hair. By varying the thickness of each layer, Shahrjerdi explained, they tuned the size and type of energy band structure, which in turn affects the properties of the material.

(a) At monolayer thickness, this material has the optical properties of a semiconductor that emits light. At multilayer, the properties change and the material doesn’t emit light. (b) Varying the thickness of each layer results in a thin film speckled with randomly occurring regions that alternately emit or block light. (c) Upon exposure to light, this pattern can be translated into a one-of-a-kind authentication key that could secure hardware components at minimal cost.

This property is unique to this material,” underscores Shahrjerdi. By tuning the material growth process, the resulting thin film is speckled with randomly occurring regions that alternately emit or do not emit light. When exposed to light, this pattern translates into a one-of-a-kind authentication key that could secure hardware components at minimal cost.

Source: http://engineering.nyu.edu/

Glass Blocks Generate Electricity Using Solar Energy

Buildings consume more than forty percent of global electricity and reportedly cause at least a third of carbon emissions. Scientists want to cut this drastically – and create a net-zero energy future for new buildings. Build Solar want to help. The firm has created a glass brick containing small solar cells.

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On top of this we have placed in some intelligent optics which are able to focus the incoming sunlight onto these solar cells almost throughout the day. When we do that we are able to generate a higher amount of electrical output from each solar cell that we are using,” says Dr Hasan Baig, founder of Build Solar.
As well as converting the sun’s power to electricity, the bricks have other abilities.
The product is aligned to provide three different things, including electricity, daylighting, and thermal insulation which is generally required by any kind of construction product. More importantly it is aesthetic in its look, so it fits in very well within the building architecture,” adds Dr Baig.
Using Building Integrated Photovoltaics, the technology would be used in addition to existing solar roof panels. The University of Exeter spin-off is fine-tuning the design, which works in many colours. The company says the product could be market ready by the end of next year.

Source: https://www.buildsolar.co.uk/

Artificial Intelligence Chip Analyzes Molecular-level Data In Real Time

Nano Global, an Austin-based molecular data company, today announced that it is developing a chip using intellectual property (IP) from Arm, the world’s leading semiconductor IP company. The technology will help redefine how global health challenges – from superbugs to infectious diseases, and cancer are conquered.

The pioneering system-on-chip (SoC) will yield highly-secure molecular data that can be used in the recognition and analysis of health threats caused by pathogens and other living organisms. Combined with the company’s scientific technology platform, the chip leverages advances in nanotechnology, optics, artificial intelligence (AI), blockchain authentication, and edge computing to access and analyze molecular-level data in real time.

In partnership with Arm, we’re tackling the vast frontier of molecular data to unlock the unlimited potential of this universe,” said Steve Papermaster, Chairman and CEO of Nano Global. “The data our technology can acquire and process will enable us to create a safer and healthier world.”

We believe the technology Nano Global is delivering will be an important step forward in the collective pursuit of care that improves lives through the application of technology,” explained Rene Haas, executive vice president and president of IPG, Arm. “By collaborating with Nano Global, Arm is taking an active role in developing and deploying the technologies that will move us one step closer to solving complex health challenges.”

Additionally, Nano Global will be partnering with several leading institutions, including Baylor College of Medicine and National University of Singapore, on broad research initiatives in clinical, laboratory, and population health environments to accelerate data collection, analysis, and product development.
The initial development of the chip is in process with first delivery expected by 2020. The company is already adding new partners to their platform.

Source: https://nanoglobal.com/
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Graphene Ripples, Clean And Limitless Energy Source

Graphene is a seemingly impossible material. For years, scientists had theorized that lifting a single layer of carbon atoms from a chunk of graphite could produce the first two-dimensional material, which they called graphene. Finally, in 2004, this was accomplished by two physicists at the University of Manchester, who earned the Nobel Prize in Physics for this breakthrough. There was a problem, however: two dimensional materials violate the laws of physics. Without the support of a substrate, physics predicts they would tear apart or melt, even at a temperature of absolute zero. Physicists had to find a loophole to explain their existence.

That loophole turned out to be related to a phenomenon known as Brownian motion, small random fluctuations of the carbon atoms that make up graphene. This causes the material to ripple into the third dimension, similar to waves moving across the surface of the ocean. These movements in and out of the flat surface allow graphene to stay comfortably within the laws of physics.

Ever since Robert Brown discovered Brownian motion in 1827, scientists have wondered whether they could harvest this motion as a source of energy. The research of Paul Thibado, professor of physics at the University of Arkansas, provides strong evidence that the motion of graphene could indeed be used as a source of clean, limitless energy. Other researchers have theorized that temperature-induced curvature inversion in graphene could be used as an energy source, and even predicted the amount of energy they could produce. What sets Thibado’s work apart is his discovery that graphene has naturally occurring ripples that invert their curvature as the atoms vibrate in response to the ambient temperature.

This is the key to using the motion of 2D materials as a source of harvestable energy,” Thibado said. Unlike atoms in a liquid, which move in a random directions, atoms connected in a sheet of graphene move together. This means their energy can be collected using existing nanotechnology.

These results have been published in the journal Physical Review Letters.

Source: https://researchfrontiers.uark.edu

New Quantum Computer Uses 10,000 Times Less Power

Japan has unveiled its first quantum computer prototype, amid a global race to build ever-more powerful machines with faster speeds and larger brute force that are key towards realising the full potential of artificial intelligence. Japan’s machine can theoretically make complex calculations 100 times faster than even a conventional supercomputer, but use just 1 kilowatt of power – about what is required by a large microwave oven – for every 10,000 kilowatts consumed by a supercomputer. Launched recently, the creators – the National Institute of Informatics, telecom giant NTT and the University of Tokyo – said they are building a cloud system to house their “quantum neural network” technology.

In a bid to spur further innovation, this will be made available for free to the public and fellow researchers for trials at https://qnncloud.com
The creators, who aim to commercialise their system by March 2020, touted its vast potential to help ease massive urban traffic congestion, connect tens of thousands of smartphones to different base stations for optimal use in a crowded area, and even develop innovative new drugs by finding the right combination of chemical compounds.

Quantum computers differ from conventional supercomputers in that they rely on theoretical particle physics and run on subatomic particles such as electrons in sub-zero temperatures. Most quantum computers, for this reason, destabilise easily and are error-prone, thereby limiting their functions.

We will seek to further improve the prototype so that the quantum computer can tackle problems with near-infinite combinations that are difficult to solve, even by modern computers at high speed,” said Stanford University Professor Emeritus Yoshihisa Yamamoto, who is heading the project.
Japan’s prototype taps into a 1km-long optical fibre cable packed with photons, and exploits the properties of light to make super-quick calculations. Its researchers said they deemed the prototype ready for public use, after tests showed that it was capable of operating stably around the clock at room temperature.

Source: http://www.straitstimes.com/

How To Detect Fluoride In Drinking Water

A simple colour-changing test to detect fluoride in drinking water, devised by researchers at the University of Bath (UK), could in the future prevent the crippling bone disease, skeletal fluorosis, in developing countries such as India and Tanzania. Whilst low amounts of fluoride are beneficial for healthy teeth, high levels of fluoride can weaken bones, leading to skeletal fluorosis. This disease causes crippling deformities of the spine and joints, especially in children whose skeletons are still forming.

When water passes over certain minerals, it can dissolve fluoride, which results in elevated levels of fluoride in drinking water sources in parts of East Africa, India, China and North America. Levels of fluoride in drinking water are routinely monitored and controlled at treatment works in developed countries. However in areas of the world where there is no piped water system or treatment works, people rely on drawing untreated water from wells, which can often be contaminated with higher than recommended levels of fluoride. The amounts of fluoride in the groundwater can vary due to weather events, with levels fluctuating hugely when there is a lot of rain.

A research team at the University of Bath’s Centre for Sustainable Chemical Technologies, and the Water Innovation and Research Centre (WIRC), led by Simon Lewis, has developed a simple colour-changing test that detects high levels of fluoride quickly and selectively. Whilst the test is at the proof of concept stage, the team aims to develop it into a disposable test strip that is low cost and easy to use by anyone.

The test changes from purple to blue when the levels of fluoride in the water are too high (click to get video)

Lewis explains: “Whilst a small amount of fluoride is good for your teeth and prevents tooth decay, high levels are toxic and can cause crippling deformities that are irreversible. “Most water quality monitoring systems need a lab and power supply and a trained operator to work them. What we’ve developed is a molecule that simply changes colour in a few minutes which can tell you whether the level of fluoride is too high. “This technology is in the very early stages, but we’d like to develop this technology into test strips, similar to litmus paper, that allow people without any scientific training to perform a test that is low cost, rapid and robust. “We anticipate that in the future it could make a real difference to people’s lives.”

I am very enthusiastic about the newly developed indicator molecules and am convinced that they can be incorporated into an easy to use technology that is able to provide instant information on the safety of drinking water with regards to fluoride,” comments co-investigator Dr Jannis Wenk, of the Department of Chemical Engineering and Water Innovation and Research Centre (WIRC) at Bath.

Source: http://www.bath.ac.uk/

Printed 3D Nanostructures Against Counterfeiting

Security features are to protect bank notes, documents, and branded products against counterfeiting. Losses caused by product forgery and counterfeiting may be enormous. According to the German Engineering Association, the damage caused in 2016 in its branch alone amounted to EUR 7.3 billion. In the Advanced Materials Technologies journal, researchers of Karlsruhe Institute of Technology (KIT) and the ZEISS company now propose to use printed 3D microstructures instead of 2D structures, such as holograms, to improve counterfeit protection.

Today, optical security features, such as holograms, are frequently based on two-dimensional microstructures,” says Professor Martin Wegener, expert for 3D printing of microstructures at the Institute of Nanotechnology of KIT. “By using 3D-printed fluorescent microstructures, counterfeit protection can be increased.” The new security features have a side length of about 100 µm and are barely visible with the eye or a conventional microscope. For their production and application, Wegener and his team have developed an innovative method that covers all processes from microstructure fabrication to the readout of information.

The microstructures consist of a 3D cross-grid scaffold and dots that fluoresce in different colors and can be arranged variably in three dimensions within this grid. To produce and print such microstructures, the experts use a rapid and precise laser lithography device developed and commercialized by the Nanoscribe company, a spinoff of KIT. It enables highly precise manufacture of voluminous structures of a few millimeters edge length or of microstructured surfaces of several cm² in dimension. The special 3D printer produces the structures layer by layer from non-fluorescent and two fluorescent photoresists. A laser beam very precisely passes certain points of the liquid photoresist. The material is exposed and hardened at the focus point of the laser beam. The resulting filigree structure is then embedded in a transparent polymer in order to protect it against damage.

Source: http://www.kit.edu/

How To Use Computers Heat To Generate Electricity

Electronic devices such as computers generate heat that mostly goes to waste. Physicists at Bielefeld University (Germany) have found a way to use this energy: They apply the heat to generate magnetic signals known as ‘spin currents’. In future, these signals could replace some of the electrical current in electronic components. In a new study, the physicists tested which materials can generate this spin current most effectively from heat. The research was carried out in cooperation with colleagues from the University of Greifswald, Gießen University, and the Leibniz Institute for Solid State and Materials Research in Dresden.

The Bielefeld physicists are working on the basic principles for making data processing more effective and energy-efficient in the young field of ‘spin caloritronics’. They are members of the ‘Thin Films & Physics of Nanostructures’ research group headed by Professor Dr. Günter Reiss. Their new study determines the strength of the spin current for various combinations of thin films.

A spin current is produced by differences in temperature between two ends of an electronic component. These components are extremely small and only one millionth of a millimetre thick. Because they are composed of magnetic materials such as iron, cobalt, or nickel, they are called magnetic nanostructures.

The physicists take two such nanofilms and place a layer of metal oxide between them that is only a few atoms thick. They heat up one of the external films – for example, with a hot nanowire or a focused laser. Electrons with a specific spin orientation then pass through the metal oxide. This produces the spin current. A spin can be conceived as electrons spinning on their own axes – either clockwise or anti-clockwise.

Their findings have been  published  in the research journal ‘Nature Communications’.

Source: https://ekvv.uni-bielefeld.de/

Polymeric Materials Outperform Natural Antibodies

Experts from the Biotechnology Group led by Professor Sergey Piletsky at the University of Leicester (UK) in collaboration with the spin-off company MIP Diagnostics Ltd, have announced the development of polymeric materials with molecular recognition capabilities which hold the potential to outperform natural antibodies in various diagnostic applications.

chemical background

 In a newly released article ‘A comparison of the performance of molecularly imprinted polymer nanoparticles for small molecule targets and antibodies in the ELISA format’ the researchers successfully demonstrated that polymer nanoparticles produced by the molecular imprinting technique (MIP nanoparticles) can bind to the target molecule with the same or higher affinity and specificity than widely used commercially available antibodies and against challenging targets.

Additionally, their ease of manufacture, short lead time, high affinity and the lack of requirement for cold chain logistics make them an attractive alternative to traditional antibodies for use in immunoassays.

Professor Piletsky, from our Department of Chemistry, explained: “It is now well over twenty years since the first demonstration that molecularly imprinted polymers can be used as the recognition material in assays for clinically significant drugs“. 

Source: https://www2.le.ac.uk/

Tesla Electric Truck Travels 500 Miles (805 km) On A Single Charge

The main course was expected: a pair of sleek silver Tesla semi-trucks that get 500 miles per charge, go from zero to 60 mph in five seconds and — if the hype is to be believed — promise to single-handedly transform the commercial trucking industry. But dessert was a surprise: A bright red prototype of the newest Tesla Roadster, a revamped version of the company’s debut vehicle that can travel from Los Angeles to San Francisco and back on a single charge and go from zero to 60 mph in under two seconds. If true, that would make the $200,000 sports car the fastest production car ever made.

On Thursday night, Tesla chief executive Elon Musk delivered both dishes to a packed crowd at the company’s design studio in Hawthorne, Calif.

What does it feel like to drive this truck?” Musk asked the audience, shortly after his latest creations rolled onto the stage. “It’s amazing! It’s smooth, just like driving a Tesla.” “It’s unlike any truck that you’ve ever driven,” he added, noting that Tesla’s big rig puts the driver at the center of the vehicle like a race car, but surrounded with touchscreen displays like those found in the Model 3. “I can drive this thing and I have no idea how to drive a semi.”

Range anxiety has always been a key concern for anyone who is weighing the purchase of an electric vehicle. Musk sought to reassure potential buyers that the company’s big rigs can match — and surpass — the performance of a diesel engine, which he referred to as “economic suicide.” Musk did not reveal the truck’s exact price, but argued that a diesel truck would be 20 cents more expensive per mile than Tesla’s electric counterpart, which will be available for purchase in 2019.

Source: https://www.washingtonpost.com/

Breathing in Delhi air equivalent to smoking 44 cigarettes a day

It was early on the morning when residents in the Indian capital of Delhi first began to notice the thick white haze that had descended across the city. Initially viewed as a mild irritant, by mid-week its debilitating effects were evident to all, as the city struggled to adapt to the new eerie, martian-like conditions brought about by the pollution.

The World Health Organization considers anything above 25 to be unsafe. That measure is based on the concentration of fine particulate matter, or PM2.5, per cubic meter. The microscopic particles, which are smaller than 2.5 micrometers in diameter, are considered particularly harmful because they are small enough to lodge deep into the lungs and pass into other organs, causing serious health risks.
With visibility severely reduced, trains have been canceled, planes delayed and cars have piled into each other, with multiple traffic accidents reported across the city. On the afternoon, city chiefs closed all public and private schools, requesting instead that the city’s tens of thousands of school-aged children remain indoors; they banned incoming trucks and halted civil construction projects; while they announced new plans to begin implementing a partial ban on private car use as of next week. But as the city woke up to a fourth straight day of heavy pollution, practical considerations were being overtaken by more serious concerns, with journalists and doctors warning residents of the long-term health implications.

Air quality readings in the Indian capital have reached frightening levels in recent days, at one point topping the 1,000 mark on the US embassy air quality index. Across the capital, doctors reported a surge in patients complaining of chest pain, breathlessness and burning eyes. “The number of patients have increased obviously,” said Deepak Rosha, a pulmonologist at Apollo Hospital, one of the largest private hospitals in Delhi. “I don’t think it’s ever been so bad in Delhi. I’m very angry that we’ve had to come to this.”
Breathing in air with a PM2.5 content of between 950 to 1,000 is considered roughly equivalent to smoking 44 cigarettes a day, according to the independent Berkeley Earth science research group.

Photovoltaics: Light Absorption Enhanced by Up to 200 Percent

Sunlight reflected by solar cells is lost as unused energy. The wings of the butterfly Pachliopta aristolochiae are drilled by nanostructures (nanoholes) that help absorbing light over a wide spectrum far better than smooth surfaces. Researchers of Karlsruhe Institute of Technology (KIT) in Germany, have now succeeded in transferring these nanostructures to solar cells and, thus, enhancing their light absorption rate by up to 200 percent.

 “The butterfly studied by us is very dark black. This signifies that it perfectly absorbs sunlight for optimum heat management. Even more fascinating than its appearance are the mechanisms that help reaching the high absorption. The optimization potential when transferring these structures to photovoltaics (PV) systems was found to be much higher than expected,” says Dr. Hendrik Hölscher of KIT’s Institute of Microstructure Technology (IMT).

 

The scientists of the team of Hendrik Hölscher and Radwanul H. Siddique (formerly KIT, now Caltech) reproduced the butterfly’s nanostructures in the silicon absorbing layer of a thin-film solar cell. Subsequent analysis of light absorption yielded promising results: Compared to a smooth surface, the absorption rate of perpendicular incident light increases by 97% and rises continuously until it reaches 207% at an angle of incidence of 50 degrees. “This is particularly interesting under European conditions. Frequently, we have diffuse light that hardly falls on solar cells at a vertical angle,” Hendrik Hölscher says. However, this does not automatically imply that efficiency of the complete PV system is enhanced by the same factor, says Guillaume Gomard of IMT. “Also other components play a role. Hence, the 200 percent are to be considered a theoretical limit for efficiency enhancement.

The scientists have reported their results in the journal Science Advances. (DOI: 10.1126/sciadv.1700232.)

Source: http://www.kit.edu/

How To Correct Genes That Cause High Cholesterol

U.S. researchers have used nanotechnology plus the powerful CRISPR-Cas9 gene-editing tool to turn off a key cholesterol-related gene in mouse liver cells, an advance that could lead to new ways to correct genes that cause high cholesterol and other liver diseasesNanotechnology is the design and manipulation of materials thousands of times smaller than the width of a human hair.

We’ve shown you can make a nanoparticle that can be used to permanently and specifically edit the DNA in the liver of an adult animal,” said study author Daniel Anderson, an associate professor in chemical engineering at the Massachusetts Institute of Technology.

The study, published  in Nature Biotechnology, holds promise for permanently editing genes such as PCSK9, a cholesterol-regulating gene that is already the target of two drugs made by the biotechnology companies Regeneron Pharmaceuticals and Amgen.

In the study, the scientists were trying to develop a safe and efficient way to deliver the components needed for CRISPR-Cas9, a type of molecular scissors that can selectively trim away defective genes and replace them with new stretches of DNA.

The system consists of a DNA-cutting enzyme called Cas9 and a stretch of RNA that guides the cutting enzyme to the correct spot in the genome. Most teams currently use viruses to deliver CRISPR into cells, an approach that is limited because the immune system can develop antibodies to viruses.

To overcome this, the team chemically modified the CRISPR components to protect them from enzymes in the body that would normally break them down. They then inserted this material into nano-scale fat particles and injected them into mice, where they made their way to liver cells.

In tests targeting the PCSK9 gene, the system proved highly effective, . The PCSK9 protein made by this gene was undetectable in the treated mice, eliminating the gene in more than 80 percent of liver cells, which also experienced a 35 percent drop in total cholesterol, the researchers reported.

High levels of cholesterol can clog arteries, causing reduced blood flow that can lead to a heart attack or stroke.

Source: http://news.mit.edu/

AI, “worst event in the history of our civilisation” says Stephen Hawking

Stephen Hawking has sent a stark warning out to the world, stating that the invention of artificial intelligence (AI) could be the “worst event in the history of our civilisation”. Speaking at the Web Summit technology conference in Lisbon, Portugal, the theoretical physicist reiterated his warning against the rise of powerful, conscious machines.
While Prof Hawking admitted that AI could be used for good, he also stated that humans need to find a way to control it so that it does not become more powerful than us as “computers can, in theory, emulate human intelligence, and exceed it.” Looking at the positives, the 75-year old said AI could help undo some of the damage that humans have inflicted on the natural world, help beat disease and “transform” every aspect of society. But, there are negatives that come with it.
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Success in creating effective AI, could be the biggest event in the history of our civilisation. Or the worst. We just don’t know. “So we cannot know if we will be infinitely helped by AI, or ignored by it and side-lined, or conceivably destroyed by it. “Unless we learn how to prepare for, and avoid, the potential risks, AI could be the worst event in the history of our civilisation. It brings dangers, like powerful autonomous weapons, or new ways for the few to oppress the many. It could bring great disruption to our economy,” explains the University of Cambridge alumni.

Prof Hawking added that to make sure AI is in line with our goals, creators need to “employ best practice and effective management.” But he still has hope: “I am an optimist and I believe that we can create AI for the good of the world. “That it can work in harmony with us. We simply need to be aware of the dangers, identify them, employ the best possible practice and management, and prepare for its consequences well in advance.”

Just last week, Prof Hawking warned that AI will replace us as the dominant being on the planet.

Source: http://www.express.co.uk/

New Genetic And Stem-Cell Technology To Grow Sheets Of Skin

Somewhere in Germany’s Ruhr valley, a nine-year-old boy is doing what children do: playing football, joking around with friends and going to school. Two years ago, he was confined to a hospital bed, dying of a rare and cruel genetic skin disease. The boy had junctional epidermolysis bullosa, or JEB. He, like other people with the disease, carried a mutation in a gene that controls the integrity of the skin. Doctors could only try to ease his suffering as some 80% of his skin simply fell away.

A team of Italian researchers came to his aid by combining stem-cell techniques with gene therapy. As a young scientist at Harvard Medical School in Boston, Massachusetts, in the 1980s, Michele De Luca — the lead author of the new study — watched pioneers in skin regeneration learn to grow small sheets of skin from cells taken from burns patients, and to use them in grafts. He extended the work in Italy, applying new genetic and stem-cell technologies. He developed ways to generate stem cells from human skin, replace disease-causing genes in them and grow sheets of healthy skin on scaffolds in the lab.

He chose JEB for his first clinical trial, which he registered with the Italian Medicines Agency in 2002. Four years later, he reported his first success, in which he created healthy skin patches from biopsies to replace small areas of sloughed-off skin on the legs of a patient with a form of JEB (F. Mavilio et al. Nature Med. 12, 1397–1402; 2006). New European Commission regulations introduced in 2007 required him to pause the project while he created facilities adhering to ‘good manufacturing practices’ (GMPs) and a spin-off company to meet the demands for strengthened oversight of cell-based therapies.

Having a company refocused his team’s attention on a different type of stem-cell therapy, one likely to yield a product for the market faster. Holoclar, a treatment that replaces the eye’s cornea in a form of blindness, became the world’s first commercial stem-cell therapy in 2015.

A few months later, at the University of Modena, De Luca got a call out of the blue from doctors in Germany who were trying to treat the little boy. Because the therapy had been in a clinical trial, albeit one on hold at the time, and because De Luca could provide GMP services, German regulatory authorities quickly approved the one-off compassionate use of the JEB therapy. Surgeons in Germany sent a skin biopsy to Modena, and two major skin transplants followed. Six months after the initial biopsy, the boy returned to school. During the many months since, he has not had so much as a blister, and loves to show off his ‘new skin’. By their nature, highly personalized treatments using gene therapies and products derived from an individual’s stem cells are likely to be applicable to only a subset of patients.

Scientists and clinicians have presented the details of the recovery in Nature (T. Hirsch et al.Nature http://dx.doi.org/10.1038/nature24487; 2017). This major clinical development was based on decades of basic research. The clinical data gathered during 21 months of follow-up after the boy’s treatment have also led to major insights into human skin biology, as discussed in an accompanying News & Views (M. Aragona and C. Blanpain Naturehttp://dx.doi.org/10.1038/nature24753; 2017). For example, normal regeneration of the epidermis is directed by only a few stem-cell clones that can self-renew.

Source: http://www.nature.com/

Sophia The Robot Says: ‘I have feelings too’

Until recently, the most famous thing that Sophia the robot had ever done was beat Jimmy Fallon a little too easily in a nationally televised game of rock-paper-scissors.

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But now, the advanced artificial intelligence robot — which looks like Audrey Hepburn, mimics human expressions and may be the grandmother of robots that solve the world’s most complex problems — has a new feather in her cap:

Citizenship.

The kingdom of Saudi Arabia officially granted citizenship to the humanoid robot last week during a program at the Future Investment Initiative, a summit that links deep-pocketed Saudis with inventors hoping to shape the future.

Sophia’s recognition made international headlines — and sparked an outcry against a country with a shoddy human rights record that has been accused of making women second-class citizens.

Source: https://www.washingtonpost.com/

Smart Paper Conducts Electricity, Detects Water

In cities and large-scale manufacturing plants, a water leak in a complicated network of pipes can take tremendous time and effort to detect, as technicians must disassemble many pieces to locate the problem. The American Water Works Association indicates that nearly a quarter-million water line breaks occur each year in the U.S., costing public water utilities about $2.8 billion annually.

A University of Washington (UW) team wants to simplify the process for discovering detrimental leaks by developing “smartpaper that can sense the presence of water. The paper, laced with conductive nanomaterials, can be employed as a switch, turning on or off an LED light or an alarm system indicating the absence or presence of water.

Water sensing is very challenging to do due to the polar nature of water, and what is used now is very expensive and not practical to implement,” said lead author Anthony Dichiara, a UW assistant professor of bioresource science and engineering in the School of Environment and Forest Sciences. “That led to the reason to pursue this work.”

Along with Dichiara, a team of UW undergraduate students in the Bioresource Science and Engineering program successfully embedded nanomaterials in paper that can conduct electricity and sense the presence of water. Starting with pulp, they manipulated the wood fibers and carefully mixed in nanomaterials using a standard process for papermaking, but never before used to make sensing papers.

Discovering that the paper could detect the presence of water came by way of a fortuitous accident. Water droplets fell onto the conductive paper the team had created, causing the LED light indicating conductivity to turn off. Though at first they thought they had ruined the paper, the researchers realized they had instead created a paper that was sensitive to water.
The researchers described their discovery in a paper appearing in the Journal of Materials Chemistry A.

Source: http://www.washington.edu/

Nanocompounds Enhance Microbial Activity On Soil, Enrich Crops

We live in a world where day to day objects seems to be getting smaller and better. The advent of nanotechnology is a major contributing factor to this phenomenon. Defined as the “engineered construction of matter at the molecular level”, nanotechnology has applications and uses in a multitude of fields. From medicine, electronics, food, clothing, batteries and environment, nanotechnology seems to be pushing the limits of all these fields. Now, scientist have discovered yet another novel application of nanotechnologyfacilitating soil microbial growth.

Indian scientists from the G. B. Pant University of Agriculture and Technology, Pantnangar, Indian Veterinary Research Institute, Izatnagar, and State Council for Science & Technology, Dehradun, studied the impact of three nanocompounds on soil microbial activity and the health of plants being cultivated.

The scientists found that supplementing agricultural soils with nanocompounds like nanoclay, nanochitosan and nanozeolite led to a higher growth of microbial populations in the soil. And such an increased microbial population further led to increased levels of phosphorus, organic carbon and nitrogen in the soils, all of which are known to improve the health of crops being cultivated. Additionally, the scientists also observed increased levels of microbial enzyme activity in the soil, as well as a 50% rise in the total protein content of the soil.

Although nanoclay had the least effect on the soil’s pH, nanozeolite was found to best facilitate the growth of soil microbes. An increase in soil microbial activity along with all the other downstream benefits, caused by these nanocompounds, are all an indicator of enhanced soil health. Therefore, supplementing soils with such nanocompounds could go a long way in improving the agricultural soils, plant health and ultimately, the crop yields of the country.

Source: http://onlinelibrary.wiley.com/

‘Internet Of Water’To Manage Floodings in U.S.

The so-called ‘internet of water‘ could be part of the solution to flooding in cities across the United States. University of Michigan researchers are piloting a ‘smart stormwater system in Ann Arbor. The system combines real-time data on how much water is in the system to help regulate water flow.

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We have a network of sensors and valves and other data we can pull in, so weather forecasts and we combine all those together to figure out when is a good time to close these valves, when is a good time to open these valves?“, says Brandon Wong, researcher at the University of Michigan.

The team can control the valves remotely using smartphone apps. Eventually this could mean the water released into the wetlands around Ann Arbor being regulated autonomously.

By also having this on the internet, it doesn’t have to be me that controls it, it could be a colleague of mine, it could be the city and it could also just be autonomous“, explains Brandon Wong. With between 10 and 20 valves per square mile of the stormwater system there’s plenty of data to monitor. The team say their smart system helps ageing infrastructure cope with the increased building pressures on green areas.

So what we have done here is making use of the remaining green areas and making them more effective by putting in these valves,” adds Wong. The project won a $1.8 million grant from the National Science Foundation. If successful, it could be rolled out across the United States.

Source: http://www-personal.umich.edu/

AI-controlled Greenhouse Uses 90 Percent Less Water To Produce Salads

Californian startup  Iron Ox runs an indoor farm complete with a few hundred plants—and two robot farmers. Instead of using technology to grow genetically modified food, a former Google engineer partnered with one of his friends who had a PhD in robotics to open a technology-based farm where they plant, seed, and grow heads of lettuce.

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Iron Ox’s goal is to provide quality produce to everyone without a premium price. According to Natural Society the average head of lettuce travels 2,055 miles from farm to market, which is why fresh lettuce is often so expensive. Currently, Iron Ox only provides produce to restaurants and grocery stores in the Bay Area of California, which is why after a daily harvest, their products are hours fresh as opposed to shipped in. The company aims to open greenhouses near other major cities, guaranteeing same-day delivery from their trucks at a fraction of the price of the current supply chain.

So why the robots? Lettuce has always been a testing ground for farming innovation, from early greenhouses to closed aquaponic ecosystems. According to Iron Ox, their AI-controlled greenhouse uses 90 percent less water than traditional farms, and because of the technology, each head of lettuce receives intimate individualized attention that is not realistic with human labor. Iron Ox also says that because they grow their products indoors with no pesticides, they don’t have to worry about typical farming issues like stray animals eating their product.

Iron Ox has yet to launch a fully-functioning automated greenhouse, but hope to build their first by the end of 2017. However, Iron Ox is not the only company to experiment with robot farming. Spread, a sustainable farming organization, broke ground on their first techno-farm, which will be fully automated and operated by robots growing lettuce, in May. They have plans to expand to the Middle East next and then continue growing.

Does this mean the future of produce is automation? Not exactly. Agriculture is complex business, and not all produce can be greenhouse-grown as efficiently and effectively as lettuce. But it’s one more reason for farmers to be aware of how the robots are coming for us all.

Source: https://www.saveur.com/

Acupuncture And Nanotechnology Married To Cure Cancer

DGIST (Daegu Gyeongbuk Institute of Science and Technology) in South Korea announced that Professor Su-Il In’s research team from the department of Energy Science and Engineering has presented the possibility of cancer treatment, including colorectal cancer, using acupuncture needles that employ nanotechnology for the first time in the world.

The research team of Professor Su-Il In, through joint research with Dr. Eunjoo Kim of Companion Diagnostics & Medical Technology Research Group at DGIST and Professor Bong-Hyo Lee’s research team from the College of Oriental Medicine at Daegu Haany University, has published a study showing that the molecular biologic indicators related to anticancer effects are changed only by the treatment of acupuncture, which is widely used in oriental medicine.

In oriental medicine, treatment using acupuncture needles has been commonly practiced for thousands of years in the fields of treating musculoskeletal disorders, pain relief, and addiction relief. Recently, it has emerged as a promising treatment for brain diseases, gastrointestinal disorders, nausea, and vomiting, and studies are under way to use acupuncture to treat severe diseases.

SURFACE IMAGES OF (A) CONVENTIONAL ACUPUNCTURE NEEDLE (CN) AND, (B) THE NANOPOROUS ACUPUNCTURE NEEDLE (PN) WITH ITS (C AND D) HIGH RESOLUTION IMAGES

Not only that, Professor In’s team discovered that acupuncture needles can be used for cancer treatment which is difficult to treat in modern medicine. In this study, the researchers developed nanoporous needles with microscopic holes in the surface of the needles ranging from nanopores (nm = one billionth of a meter) to micrometers (μm = one millionth of a meter) by applying relatively simple electrochemical nanotechnology. By increasing the surface area of the needle by a factor of ten, the nanoporous needles doubled the electrophysiological signal generation function by needle stimulus.

As a result of AOM administration in rats, the rats receiving periodic acupuncture treatment with nanoporous needles were found to have a much lower incidence of abnormal vascular clusters as a precursor to colorectal cancer in the initiation stage than those in the control group.

Source: https://www.eurekalert.org/

Thin Films Power Electronics Mixed In Fabrics

Scientists at the U.S. Department of Energy’s National Renewable Energy Laboratory (NREL) reported significant advances in the thermoelectric performance of organic semiconductors based on carbon nanotube thin films that could be integrated into fabrics to convert waste heat into electricity or serve as a small power source.

The research demonstrates significant potential for semiconducting single-walled carbon nanotubes (SWCNTs) as the primary material for efficient thermoelectric generators, rather than being used as a component in a “compositethermoelectric material containing, for example, carbon nanotubes and a polymer. The discovery is outlined in the new Energy & Environmental Science paper, Large n- and p-type thermoelectric power factors from doped semiconducting single-walled carbon nanotube thin films.

There are some inherent advantages to doing things this way,” said Jeffrey Blackburn, a senior scientist in NREL’s Chemical and Materials Science and Technology center and co-lead author of the paper with Andrew Ferguson. These advantages include the promise of solution-processed semiconductors that are lightweight and flexible and inexpensive to manufacture. Other NREL authors are Bradley MacLeod, Rachelle Ihly, Zbyslaw Owczarczyk, and Katherine Hurst. The NREL authors also teamed with collaborators from the University of Denver and partners at International Thermodyne, Inc., based in Charlotte, N.C.

Ferguson, also a senior scientist in the Chemical and Materials Science and Technology center, said the introduction of SWCNT into fabrics could serve an important function for “wearable” personal electronics. By capturing body heat and converting it into electricity, the semiconductor could power portable electronics or sensors embedded in clothing.

Source: https://www.nrel.gov/

Invisible Glass

If you have ever watched television in anything but total darkness, used a computer while sitting underneath overhead lighting or near a window, or taken a photo outside on a sunny day with your smartphone, you have experienced a major nuisance of modern display screens: glare. Most of today’s electronics devices are equipped with glass or plastic covers for protection against dust, moisture, and other environmental contaminants, but light reflection from these surfaces can make information displayed on the screens difficult to see. Now, scientists at the Center for Functional Nanomaterials (CFN) — a U.S. Department of Energy Office of Science User Facility at Brookhaven National Laboratory — have demonstrated a method for reducing the surface reflections from glass surfaces to nearly zero by etching tiny nanoscale features into them.

Whenever light encounters an abrupt change in refractive index (how much a ray of light bends as it crosses from one material to another, such as between air and glass), a portion of the light is reflected. The nanoscale features have the effect of making the refractive index change gradually from that of air to that of glass, thereby avoiding reflections. The ultra-transparent nanotextured glass is antireflective over a broad wavelength range (the entire visible and near-infrared spectrum) and across a wide range of viewing angles. Reflections are reduced so much that the glass essentially becomes invisible.

This “invisible glass” could do more than improve the user experience for consumer electronic displays. It could enhance the energy-conversion efficiency of solar cells by minimizing the amount of sunlight lost to refection. It could also be a promising alternative to the damage-prone antireflective coatings conventionally used in lasers that emit powerful pulses of light, such as those applied to the manufacture of medical devices and aerospace components.

We’re excited about the possibilities,” said CFN Director Charles Black, corresponding author on the paper published online on October 30 in Applied Physics Letters. “Not only is the performance of these nanostructured materials extremely high, but we’re also implementing ideas from nanoscience in a manner that we believe is conducive to large-scale manufacturing.”

Our role in the CFN is to demonstrate how nanoscience can facilitate the design of new materials with improved properties,” concluded Black. “This work is a great example of that–we’d love to find a partner to help advance these remarkable materials toward technology.”

Source: https://www.eurekalert.org/

Robots Soon Will Share Our Private And Sex Life

Sex robot inventor Sergi Santos isn’t just changing how men pleasure themselves — he’s potentially changing society as we know it. The Spanish scientist believes it’s only a matter of time before human-and-robot marriage is commonplace, and he’s even hatched a plan for how he can have a baby with his mechanical temptress SamanthaSamantha is Santos’ 100-pound sex robot that boasts eight different programs and the ability to make “realistic” orgasm sounds.

Santos said he believes that in the next couple of decades, we won’t just be seeing these dolls hidden in a man’s closet or under the bed — they’ll be walking down the aisle to say “I do” to their human lovers.

Speaking from his home laboratory in Barcelona (Spain), he said: “People might look at Samantha as a weird thing you read about.” “But before they know it, these robots will be doing their jobs, and marrying their children, their grandchildren, and their friends.” “They need to remember that just a few years ago, mobile phones were seen as a non-essential item in society, but now we can’t function without them.” And Santos claims he will soon be able to have a baby with Samantha. He explained: “I can make them have a baby. It’s not so difficult. I would love to have a child with a robot.” His plan involves using thebrain” he has created for Samantha but upgrading it so it is functioning at full capability.

Source: http://nypost.com/
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Editing Genes In Human Embryos

Two new CRISPR tools overcome the scariest parts of gene editing.The ability to edit RNA and individual DNA base pairs will make gene editing much more precise. Several years ago, scientists discovered a technique known as CRISPR/Cas9, which allowed them to edit DNA more efficiently than ever before.
Since then, CRISPR science has exploded; it’s become one of the most exciting and fast-moving areas of research, transforming everything from medicine to agriculture and energy. In 2017 alone, more than 14,000 CRISPR studies were published.

But here’s the thing: CRISPR, while a major leap forward in gene editing, can still be a blunt instrument. There have been problems with CRISPR modifying unintended gene targets and making worrisome, and permanent, edits to an organism’s genome. These changes could be passed down through generations, which has raised the stakes of CRISPR experiments — and the twin specters of “designer babies” and genetic performance enhancers — particularly when it comes to editing genes in human embryos.
So while CRISPR science is advancing quickly, scientists are still very much in the throes of tweaking and refining their toolkit. And on Wednesday, researchers at the Broad Institute of MIT and Harvard launched a coordinated blitz with two big reports that move CRISPR in that safer and more precise direction.
In a paper published in Science, researchers described an entirely new CRISPR-based gene editing tool that targets RNA, DNA’s sister, allowing for transient changes to genetic material. In Nature, scientists described how a more refined type of CRISPR gene editing can alter a single bit of DNA without cutting it — increasing the tool’s precision and efficiency.

The first paper, out Wednesday in Science, describes a new gene editing system. This one, from researchers at MIT and Harvard, focuses on tweaking human RNA instead of DNA.

Our cells contain chromosomes made up of chemical strands called DNA, which carry genetic information. Those genes have recipes for proteins that lead to a bunch of different traits. But to carry out the instructions in any one recipe, DNA needs another type of genetic material called RNA to get involved.

RNA is ephemeral: It acts like a middleman, or a messenger. For a gene to become a protein, that gene has to be transcribed into RNA in the cell, and the RNA is then read to make the protein. If the DNA is permanent — the family recipe book passed down through generations — the RNA is like your aunt’s scribbled-out recipe on a Post-It note, turning up only when it’s needed and disappearing again.

With the CRISPR/Cas9 system, researchers are focused on editing DNA. (For more on how that system works, read this Vox explainer.) But the new Science paper describes a novel gene editing tool called REPAIR that’s focused on using a different enzyme, Cas13, to edit that transient genetic material, the RNA, in cells. REPAIR can target specific RNA letters, or nucleosides, that are involved in single-base changes that regularly cause disease in humans.

This is hugely appealing for one big reason: With CRISPR/Cas9, the changes to the genome, or the cell’s recipe book, are permanent. You can’t undo them. With REPAIR, since researchers can target single bits of ephemeral RNA, the changes they make are transient, even reversible. So this system could fix genetic mutations without actually touching the genome (like throwing away your aunt’s Post-It note recipe without adding it to the family recipe book).

Source: https://www.vox.com/

How To Detect Lead In Water

Gitanjali Rao, 11-year-old girl, is “America’s Top Young Scientist” of this year, with her invention of Tethys, a device that detects lead in water.

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Tethys, the Greek goddess of fresh water, is a lead detection tool. What you do is first dip a disposable cartridge, which can easily be removed and attached to the core device in the water you wish to test. Once you do that, that’s basically the manual part. Then you just pull out an app on your phone and check your status and it looks like the water in this container is safe. So that’s just very simple, about like a 10 to 15 second process,” says Gitanjali Rao . The young girl was affected by the Flint, Michigan water catastrophe when the city started using the Flint River for water in 2014, sparking a crisis that was linked to an outbreak of Legionnaires’ disease, at least 12 deaths and dangerously high lead levels in children.

I was most affected about Flint, Michigan because of the amount of people that were getting affected by the lead in water. And I also realized that it wasn’t just in Flint, Michigan and there were over 5,000 water systems in the U.S. alone. In the beginning of my final presentation at the event, I talked about a little boy named Opemipo, he’s 10 years old and lives in Flint, Michigan. And he has 1 percent elevated lead levels in his blood. And he’s among the thousands of adults and children exposed to the harmful effects of lead in water. So it’s a pretty big deal out there today,” remembers Rao. The seventh-grader said it took her five months to make Tethys from start to finish.

My first couple of times when I was doing my experimentation and test, I did fail so many times and it was frustrating, but I knew that it was just a learning experience and I could definitely develop my device further by doing even more tests and getting advice from my mentor as well. So, never be afraid to try,” explains Rao, who  won the 2017 Discovery Education 3M Young Scientist Challenge, along with a $25,000 prize.

Source: http://www.reuters.com/

Self-regulating Nanoparticles Treat Cancer

Scientists from the University of Surrey have developed ‘intelligentnanoparticles which heat up to a temperature high enough to kill cancerous cells – but which then self-regulate and lose heat before they get hot enough to harm healthy tissue. The self-stopping nanoparticles could soon be used as part of hyperthermic-thermotherapy to treat patients with cancer, according to an exciting new study reported in NanoscaleThermotherapy has long been used as a treatment method for cancer, but it is difficult to treat patients without damaging healthy cells. However, tumour cells can be weakened or killed without affecting normal tissue if temperatures can be controlled accurately within a range of 42°C to 45°C.

Scientists from Surrey’s Advanced Technology Institute have worked with colleagues from the Dalian University of Technology in China to create nanoparticles which, when implanted and used in a thermotherapy session, can induce temperatures of up to 45°C. The Zn-Co-Cr ferrite nanoparticles produced for this study are self-regulating, meaning that they self-stop heating when they reach temperatures over 45°C. Importantly, the nanoparticles are also low in toxicity and are unlikely to cause permanent damage to the body.

This could potentially be a game changer in the way we treat people who have cancer. If we can keep cancer treatment sat at a temperature level high enough to kill the cancer, while low enough to stop harming healthy tissue, it will prevent some of the serious side effects of vital treatment. It’s a very exciting development which, once again, shows that the University of Surrey research is at the forefront of nanotechnologies – whether in the field of energy materials or, in this case, healthcare,” said Professor Ravi Silva, Head of the Advanced Technology Institute at the University of Surrey.

Dr. Wei Zhang, Associate Professor from Dalian University of Technology explains: “Magnetic induced hyperthermia is a traditional route of treating malignant tumours. However, the difficulties in temperature control has significantly restricted its usage If we can modulate the magnetic properties of the nanoparticles, the therapeutic temperature can be self-regulated, eliminating the use of clumsy temperature monitoring and controlling systems.

“By making magnetic materials with the Curie temperature falling in the range of hyperthermia temperatures, the self-regulation of therapeutics can be achieved. For the most magnetic materials, however, the Curie temperature is much higher than the human body can endure. By adjusting the components as we have, we have synthesized the nanoparticles with the Curie temperature as low as 34oC. This is a major nanomaterials breakthrough.”

Source: https://www.surrey.ac.uk/

Using Brain-Machine Interfaces, Mental Power Can Move Objects

A unique citizen science project in which volunteers will be trained to move a piece of steel machinery using the power of their mind begins on October 27. The Mental Work project uses brain-machine interfaces developed at EPFL (Ecole polytechnique fédérale de Lausanne) in Switzerland, a convergence of science, art, and design .

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At the mental work factory the public can come and we equip them with an EEG helmet which will read the mental activity, the electrical activity, that’s in their brain. These helmets are dry, so we don’t need gel for conductivity and they’re also wireless so they can walk through the mental factory and engage with four of our machines activating them with only their mental activity,  explains Michael Mitchell , who is one of the three co-founders of Mental Work.

The data that will be collected during the mental worker’s trajectory throughout our factory floor will then be made anonymous and given to the brain machine interface community to improve the interfaces for the future. “We think that we’re on the cusp of a cognitive revolution. Now a cognitive revolution is going to be a world where our brains are intimately connected to our physical world around us. With the development of these brain machine interfaces we think that we are really at the beginning of a moment in time where man is going to become the centre of all this technology. His brain activity is going to interact with the physical world around him in ways that we can hardly imagine today. “So I think it’s understandable if people are a little apprehensive about this technology because some people may think ‘oh, it can read my thoughts and then what are we going to do with those thoughts. Where’s the privacy level here?’ But in fact we’re only asking you to modulate your brain activity according to your own will. So it’s as simple as sending a command to a computer using a mouse or a keyboard. But this time we’re using asking you to use your brain. Now we want to bring this technology to the public at a early phase of its development so that we can create a dialogue about what kind of relationship we want to have with this technology in particular but also with man’s relationship to technology in general.

Source: https://actu.epfl.ch/

Ultra-fast Data Processing At Nanoscale

Advancement in nanoelectronics, which is the use of nanotechnology in electronic components, has been fueled by the ever-increasing need to shrink the size of electronic devices like nanocomputers in a bid to produce smaller, faster and smarter gadgets such as computers, memory storage devices, displays and medical diagnostic tools.

While most advanced electronic devices are powered by photonics – which involves the use of photons to transmit informationphotonic elements are usually large in size and this greatly limits their use in many advanced nanoelectronics systems. Plasmons, which are waves of electrons that move along the surface of a metal after it is struck by photons, holds great promise for disruptive technologies in nanoelectronics. They are comparable to photons in terms of speed (they also travel with the speed of light), and they are much smaller. This unique property of plasmons makes them ideal for integration with nanoelectronics. However, earlier attempts to harness plasmons as information carriers had little success.

Addressing this technological gap, a research team from the National University of Singapore (NUS) has recently invented a novel “converter” that can harness the speed and small size of plasmons for high frequency data processing and transmission in nanoelectronics.

This innovative transducer can directly convert electrical signals into plasmonic signals, and vice versa, in a single step. By bridging plasmonics and nanoscale electronics, we can potentially make chips run faster and reduce power losses. Our plasmonic-electronic transducer is about 10,000 times smaller than optical elements. We believe it can be readily integrated into existing technologies and can potentially be used in a wide range of applications in the future,” explained Associate Professor Christian Nijhuis from the Department of Chemistry at the NUS Faculty of Science, who is the leader of the research team behind this breakthrough.

This novel discovery was first reported in the journal Nature Photonics.

Source: http://news.nus.edu.sg/

3D Printed Concrete Bridge

Today world’s first 3D printed reinforced, pre-stressed concrete bridge was opened. The cycle bridge is part of a new road around the village of Gemert, in the Netherlands. It was printed at Eindhoven University of Technology. With the knowledge the researchers gained in this project, they are now able to design even larger printed concrete structures.
The bridge is the first civil infrastructure project to be realized with 3D-concrete printing. The bridge is 8 meters long (clear span 6.5 meters) and 3.5 meters wide. As it is a ‘worlds first’, the developers did not take any chances and tested the bridge by putting a load of 5 tons on it, which is a lot more than the load the bridge will actually carry.

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The bridge has to meet all regular requirements of course. It is designed to do its duty – to carry cyclists – for thirty years or more. With more cycles than people in the Netherlands, it is expected that hundreds of cyclists will ride over the printed bridge every day. It is part of a large road construction project, led by the company BAM Infra, and commissioned by the province of North-Brabant.
An important detail is that the researchers at Eindhoven University of Technology have succeeded in developing a process to incorporate steel reinforcement cable while laying a strip of concrete. The steel cable is the equivalent of the reinforcement mesh used in conventional concrete. It handles the tensile stress because concrete cannot deal with tensile stress adequately, but steel can.
One of the main advantages of printing concrete is that much less concrete is needed than in the conventional technique, in which a mold (formwork) is filled with concrete. By contrast, the printer deposits only the concrete where it is needed, which decreases the use of cement. This reduces CO2 emissions, as cement production has a very high carbon footprint.

Another benefit lies in the freedom of form: the printer can make any desired shape, whereas conventional concrete shapes tend to be unwieldy in shape due to use of formwork. Concrete printing also enables a much higher realization speed. No formwork structures have to be built and dismantled, and reinforcement mesh does not have to be put in place separately. Overall, the researchers think the realization will eventually be roughly three times faster than conventional concrete techniques.

Source: https://www.tue.nl/

Dyslexia Coud Be Definitively Cured

French scientists from the University of Rennes say they may have found a potential cause of dyslexia which could be treatable, hidden in tiny cells in the human eye. In a small study they found that most dyslexics had dominant round spots in both eyes – rather than in just one – leading to blurring and confusion. UK experts said the research was “very exciting” and highlighted the link between vision and dyslexia.

Not all dyslexics are likely to have the same problem. People with dyslexia have difficulties learning to read, spell or write despite normal intelligence. Often letters appear to move around and get in the wrong order and dyslexic people can have problems distinguishing left from right. Human beings have a dominant eye in the same way that people have a dominant left or right hand.
In the University of Rennes study, published in the journal Proceedings of the Royal Society B, scientists looked into the eyes of 30 non-dyslexics and 30 dyslexics.
They discovered differences in the shape of spots deep in the eye where red, green and blue cones – responsible for colour – are located. In non-dyslexics, they found that the blue cone-free spot in one eye was round and in the other eye it was oblong or unevenly shaped, making the round one more dominant. But in dyslexic people, both eyes had the same round-shaped spot, which meant neither eye was dominant. This would result in the brain being confused by two slightly different images from the eyes.

Researchers Guy Ropars and Albert le Floch said this lack of asymmetry “might be the biological and anatomical basis of reading and spelling disabilities“. They added: “For dyslexic students, their two eyes are equivalent and their brain has to successively rely on the two slightly different versions of a given visual scene.”

Source: http://www.bbc.com/

Gene Researchers Have Created Green Mice

These are no Frankenstein mice. Their green feet come courtesy of a fluorescent green jelly fish gene added to their own genome. This allows a team of British scientists to test out gene editing using CRISPR-Cas9 technology.

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“We take what were or would have been green embryos and we make them into non-green embryos, so it’s a really great way of demonstrating the method“, said Dr. Anthony Perry, reproductive biologist at the University of Bath.

The technique uses the ribonucleic acid molecule CRISPR together with the Cas9 protein enzyme. CRISPR guides the Cas9 protein to a defective part of a genome where it acts like molecular scissors to cut out a specific part of the DNA. This could revolutionise how we treat diseases with a genetic component, like sickle cell anaemia. The technique is being pioneered in the U.S.
We now have a technology that allows correction of a sequence that would lead to normally functioning cells. And I think you know the opportunities with this are really exciting and really profound. There are many diseases that are have known genetic causes that we now have in principle a way to cure,“explains Jennifer Doudna, Professor of cell biology at the University of Berkeley.
Last year two teams of U.S. based scientists used CRISPR-Cas9 technology in mice to correct the genetic mutation that causes sickle cell disease. Although researchers aren’t yet close to using CRISPR-Cas9 to edit human embryos for implantation into the womb – some are already warning against it.

Dr David King, Director of  Human Genetics Alert, comments: “It will immediately create this new form of what we call consumer eugenics, that’s to say eugenics driven by the free market and consumer preferences in which people choose the cosmetic characteristics and the abilities of their children and try to basically enhance their children to perform better than other people’s children.” Other potential applications of the technology could be to make food crops and livestock animal species disease-resistant. The British team say CRISPR-Cas9 presents a golden opportunity to prevent genetic disease.

Source: http://www.reuters.com/
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Lab-grown Diamonds

This shiny, sparkly diamond was made inside a laboratory – but it has the same chemical makeup as its counterpart found deep inside the earth.

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All the composition is exactly the same. It is a real diamond. What we’ve done is we’ve just taken what’s happened in nature and just put it in a lab,” said  Kelly Good, Director of Marketing of Pure Grown Diamonds.

Essentially, all diamonds are carbon. And inside a laboratory, scientists are using a method called microwave plasma chemical vapour deposition to grow the stones from a diamond seed. They do it by creating a plasma ball made of hydrogen inside a growth chamber. Methane, which is a carbon source, is added. The carbon mix rains down on the diamond seeds, layer by layer, creating a large, rough diamond that is cut and polished. The process takes about 10 to 12 weeks. Marketers tout the lab-grown diamonds as an eco-friendly, conflict-free alternative to mined diamonds. “Our consumer is millennials, anybody who is getting engaged are really buying the lab-grown diamonds. They also like the fact of the environmental aspect of it. That it’s grown in a greenhouse. There is less soil being moved. We have a less carbon footprint,” explains Kelly Good.

While similar in appearance, there are differences. David Weinstein, Executive Director of the International  Gemological Institute (New York), comments: “I have a crystal, a diamond and I’m looking at it and I see a peridot crystal, a green peridot crystal, I know right away, this wasn’t created in a machine. So the inclusions can really be very telling as to what the origins of the material is. And that’s what our gemologists look for.”
While lab-grown gems have been around for decades, but it’s only recently that the science and technology have made it possible to grow large, gem quality stones. And according to a report by Morgan Stanley, the lab-grown diamond market could grow by about 15 percent by the year 2020.

Source: http://www.reuters.com/

How To Clean Nuclear Waste

Cleaning up radioactive waste is a dangerous job for a human. That’s why researchers at the University of  Manchester are developing robots that could do the job for us. Five years ago, in 2011, a major earthquake and tsunami devastated the east coast of Japan, leading to explosions and subsequent radiation release at the Fukushima Daiichi Nuclear Power Station. The fuel in three of the reactors is believed to have melted, causing a large amount of contaminated water on site.

This is still to be dealt with today – which isn’t too surprising, given that the clean-up of Chernobyl is still underway 30 years after the infamous nuclear accident took place. After the accident at Chernobyl, where an extremely high level of radiation was released, workers had to be sent into areas to which you wouldn’t want to send a human being. For the safety of others, they entered the plant to survey its condition, extinguish fires and manually operate equipment and machinery – all in an environment that endangered their lives. The challenge in dismantling the site at Fukushima is the residual radiation level. In the surrounding areas levels have fallen significantly; in some places (still off limits to former residents) radiation levels actually aren’t very different from natural background levels in certain other parts of the world. But in the reactor itself a person would receive a lethal dose of radiation almost instantly.

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At Fukushima, many of the instrumentation systems, such as reactor-water level and reactor pressure, were lost in the incident. This made assessing the integrity of the plant extremely difficult as you couldn’t send people to go and look at it,” explains Professor Barry Lennox, who, alongside Dr Simon Watson at The University of Manchester, is working to find another way of getting access to such dangerous places: by using robots. Professor Lennox and Dr Watson are part of a team working to adapt robots to help clean up Fukushima. They’re developing an underwater remote-operated vehicle – the AVEXIS – to help identify highly radioactive nuclear fuel that is believed to be dispersed underwater in the damaged reactor. The robot is already aiding decommissioning efforts at Sellafield, where it will swim around the ponds storing legacy waste to map and monitor the conditions within them.

Source: https://www.manchester.ac.uk/

How To Charge Lithium Batteries 20 Times Faster

A touch of asphalt may be the secret to high-capacity lithium metal batteries that charge 10 to 20 times faster than commercial lithium-ion batteries, according to Rice University scientists. The Rice lab of chemist James Tour developed anodes comprising porous carbon made from asphalt that showed exceptional stability after more than 500 charge-discharge cycles. A high-current density of 20 milliamps per square centimeter demonstrated the material’s promise for use in rapid charge and discharge devices that require high-power density.

Scanning electron microscope images show an anode of asphalt, graphene nanoribbons and lithium at left and the same material without lithium at right. The material was developed at Rice University and shows promise for high-capacity lithium batteries that charge 20 times faster than commercial lithium-ion batteries

The capacity of these batteries is enormous, but what is equally remarkable is that we can bring them from zero charge to full charge in five minutes, rather than the typical two hours or more needed with other batteries,” Tour said.

The Tour lab previously used a derivative of asphalt — specifically, untreated gilsonite, the same type used for the battery — to capture greenhouse gases from natural gas. This time, the researchers mixed asphalt with conductive graphene nanoribbons and coated the composite with lithium metal through electrochemical deposition. The lab combined the anode with a sulfurized-carbon cathode to make full batteries for testing. The batteries showed a high-power density of 1,322 watts per kilogram and high-energy density of 943 watt-hours per kilogram.

Testing revealed another significant benefit: The carbon mitigated the formation of lithium dendrites. These mossy deposits invade a battery’s electrolyte. If they extend far enough, they short-circuit the anode and cathode and can cause the battery to fail, catch fire or explode. But the asphalt-derived carbon prevents any dendrite formation.

The finding is reported in the American Chemical Society journal ACS Nano.

Source: http://news.rice.edu/

How To Track Blood Flow In Tiny Vessels

Scientists have designed gold nanoparticles, no bigger than 100 nanometres, which can be coated and used to track blood flow in the smallest blood vessels in the body. By improving our understanding of blood flow in vivo the nanoprobes represent an opportunity to help in the early diagnosis of diseaseLight microscopy is a rapidly evolving field for understanding in vivo systems where high resolution is required. It is particularly crucial for cardiovascular research, where clinical studies are based on ultrasound technologies which inherently have lower resolution and provide limited information.

The ability to monitor blood flow in the sophisticated vascular tree (notably in the smallest elements of the microvasculaturecapillaries) can provide invaluable information to understand disease processes such as thrombosis and vascular inflammation. There are further applications for the improved delivery of therapeutics, such as targeting tumours.

Currently, blood flow in the microvasculature is poorly understood. Nanoscience is uniquely placed to help understand the processes happening in the micron-dimensioned vessels. Designing probes to monitor blood flow is challenging because of the environment; the high protein levels in plasma and the high red blood cell concentrations are detrimental to optical imaging. Conventional techniques rely on staining red blood cells, using organic dyes with short-lived usage due to photobleaching, as the tracking motif. The relatively large size of the red blood cells (7-8 micrometres), which are effectively the probes, limits the resolution in imaging and analysis of flow dynamics of the smallest vessels which are of a similar width. Therefore, to have more detailed resolution and information about the blood flow in the microvasculature, even smaller probes are required.

The key to these iridium-coated nanoparticles lies in both their small size, and in the characteristic luminescent properties. The iridium gives a luminescent signal in the visible spectrum, providing an optical window which can be detected in blood. It is also long-lived compared to organic fluorophores, while the tiny gold particles are shown to be ideal for tracking flow and detect clearly in tissues“, explains Professor Zoe Pikramenou, from the School of Chemistry at  the University of Birmingham.

The findings have been published in the journal Nanomedicine.

Source: https://www.birmingham.ac.uk/

Within 10 years Planes Could Move Up To 10 Times The Speed Of Sound

An average flight from Miami to Seattle takes about six hours and 40 minutes, but imagine being able to reduce that time to 50 minutes or less. A recent study by NASA and Binghamton University researchers could lead to a drastic decrease in flight times. The study, funded in part by the U.S. Air Force, is one of the first steps toward the creation of planes able to move at hypersonic speeds, five to 10 times the speed of soundBinghamton University Associate Professor of Mechanical Engineering Changhong Ke explained that there are currently quite a few obstacles when it comes to building these super planes. The first of which is finding a material that can hold up to hypersonic travel.

Our study used what are called boron nitride nanotubes (BNNTs). NASA currently owns one of the few facilities in the world able to produce quality BNNTs.” Typically, carbon nanotubes have been used in planes for their strength — they’re stronger than steel — and their ability to conduct heat. However, BNNTs are the wave of the future when it comes to air travel. “While carbon nanotubes can stay stable at temperatures up to 400 degrees Celsius, our study found that BNNTs can withstand up to 900 degrees Celsius,” said Ke. BNNTs are also able to handle high amounts of stress and are extremely lightweight.

Withstanding high temperatures is an important requirement for any material meant to build the world’s next super planes, however, Ke clarified that the material has to be able to maintain both structural and mechanical properties in an oxygen environment. “We weren’t testing this material in a vacuum like what you would experience in space. Materials can withstand much higher temperatures in space. We wanted to see if BNNTs could hold up in the type of environment an average fighter jet or commercial plane would experience.”

While the study has brought new light to the strength and stability of BNNTs, their use on planes may not be a reality for another five to 10 years. “Right now, BNNTs cost about $1,000 per gram. It would be impractical to use a product that expensive,” added Ke. But, that does not mean it will never happen. Carbon nanotubes were about the same price 20 years ago. As more studies indicated the usefulness of carbon nanotubes, the production rates increased and prices went down to the current rate, between $10 and $20 per gram. Ke sees the same fate coming down the line for BNNTs.

Source: https://www.binghamton.edu/

How To Extract Hydrogen Fuel from Seawater

It’s possible to produce hydrogen to power fuel cells by extracting the gas from seawater, but the electricity required to do it makes the process costly. UCF researcher Yang Yang from the University of Central Florida (UCF)  has come up with a new hybrid nanomaterial that harnesses solar energy and uses it to generate hydrogen from seawater more cheaply and efficiently than current materials. The breakthrough could someday lead to a new source of the clean-burning fuel, ease demand for fossil fuels and boost the economy of Florida, where sunshine and seawater are abundant. Yang, an assistant professor with joint appointments in the University of Central Florida’s NanoScience Technology Center and the Department of Materials Science and Engineering, has been working on solar hydrogen splitting for nearly 10 years.

It’s done using a photocatalyst – a material that spurs a chemical reaction using energy from light. When he began his research, Yang focused on using solar energy to extract hydrogen from purified water. It’s a much more difficulty task with seawater; the photocatalysts needed aren’t durable enough to handle its biomass and corrosive salt.

We’ve opened a new window to splitting real water, not just purified water in a lab,” Yang said. “This really works well in seawater.”

As reported in the journal Energy & Environmental Science, Yang and his research team have developed a new catalyst that’s able to not only harvest a much broader spectrum of light than other materials, but also stand up to the harsh conditions found in seawater.

 

Source: https://today.ucf.edu/

How To Fix Duchenne Muscular Dystrophy

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease. A new study shows that a single injection of CRISPR-Gold, as the new delivery system is called, into mice with Duchenne muscular dystrophy led to an 18-times-higher correction rate and a two-fold increase in a strength and agility test compared to control groups.

Since 2012, when study co-author Jennifer Doudna, a professor of molecular and cell biology and of chemistry at UC Berkeley, and colleague Emmanuelle Charpentier, of the Max Planck Institute for Infection Biology, repurposed the Cas9 protein to create a cheap, precise and easy-to-use gene editor, researchers have hoped that therapies based on CRISPR-Cas9 would one day revolutionize the treatment of genetic diseases. Yet developing treatments for genetic diseases remains a big challenge in medicine. This is because most genetic diseases can be cured only if the disease-causing gene mutation is corrected back to the normal sequence, and this is impossible to do with conventional therapeutics.

CRISPR/Cas9, however, can correct gene mutations by cutting the mutated DNA and triggering homology-directed DNA repair. However, strategies for safely delivering the necessary components (Cas9, guide RNA that directs Cas9 to a specific gene, and donor DNA) into cells need to be developed before the potential of CRISPR-Cas9-based therapeutics can be realized. A common technique to deliver CRISPR-Cas9 into cells employs viruses, but that technique has a number of complications. CRISPR-Gold does not need viruses.

In the new study, research lead by the laboratories of Berkeley bioengineering professors Niren Murthy and Irina Conboy demonstrated that their novel approach, called CRISPR-Gold because gold nanoparticles are a key component, can deliver Cas9 – the protein that binds and cuts DNA – along with guide RNA and donor DNA into the cells of a living organism to fix a gene mutation.

CRISPR-Gold is the first example of a delivery vehicle that can deliver all of the CRISPR components needed to correct gene mutations, without the use of viruses,” Murthy said.

The study was published in the journal Nature Biomedical Engineering.

Source: http://news.berkeley.edu/

Paper Supercapacitor

By coating ordinary paper with layers of gold nanoparticles and other materials, researchers have fabricated flexible paper supercapacitors that exhibit the best performance of any textile-type supercapacitor to date. In particular, the paper supercapacitors address one of the biggest challenges in this area, which is to achieve a high energy density in addition to an already high power density, since both properties are essential for realizing high-performance energy-storage devices. In the future, flexible paper supercapacitors could be used in wearable electronics for biomedical, consumer, and military applications. The researchers, led by Seung Woo Lee at the Georgia Institute of Technology and Jinhan Cho at Korea University, have published a paper on the flexible paper supercapacitor electrodes in a recent issue of Nature Communications. As energy-storage devices, supercapacitors have several advantages over batteries, such as a higher power density, rapid charge/discharge rate, and longer lifetime, yet they lag behind batteries in energy density (the amount of energy that can be stored in a given amount of space). Although several methods have been attempted to improve the energy density of paper supercapacitors by coating them with various conductive materials, often these methods have the drawback of reducing the power density.

The paper electrodes based on layer-by-layer-assembled metal nanoparticles exhibit metal-like electric conductivity, paper-like mechanical properties, and a large surface area without any thermal treatment and/or mechanical pressing,” explains coauthor Yongmin Ko at Korea University. “The periodic insertion of metal nanoparticles within high-energy nanoparticle-based paper electrodes could resolve the critical tradeoff in which an increase in the loading amount of materials to enhance the energy density of supercapacitors decreases the power density.”
Tests  showed that the flexible paper supercapacitors had a maximum capacitance that is higher than any previously reported textile-based supercapacitor. In addition, the new devices exhibits an excellent capacity retention, demonstrated by a 90% capacity retention after 5,000 bending cycles.

Source: http://me.gatech.edu/

One-Two Knockout Punch To Eradicate Super Bugs

Light-activated nanoparticles, also known as quantum dots, can provide a crucial boost in effectiveness for antibiotic treatments used to combat drug-resistant superbugs such as E. coli and Salmonella, new CU Boulder research shows. Multi-drug resistant pathogens, which evolve their defenses faster than new antibiotic treatments can be developed to treat them, cost the United States an estimated $20 billion in direct healthcare costs and an additional $35 billion in lost productivity in 2013. Rather than attacking the infecting bacteria conventionally, the dots release superoxide, a chemical species that interferes with the bacteria’s metabolic and cellular processes, triggering a fight response that makes it more susceptible to the original antibiotic.

We’ve developed a one-two knockout punch,” said Prashant Nagpal, an assistant professor in CU Boulder’s Department of Chemical and Biological Engineering (CHBE) and the co-lead author of the study. “The bacteria’s natural fight reaction [to the dots] actually leaves it more vulnerable.”

We are thinking more like the bug,” explains Anushree Chatterjee, an assistant professor in CHBE and the co-lead author of the study. “This is a novel strategy that plays against the infection’s normal strength and catalyzes the antibiotic instead.” The dots reduced the effective antibiotic resistance of the clinical isolate infections by a factor of 1,000 without producing adverse side effects.

The findings have been published today in the journal Science Advances.

Source: http://www.colorado.edu/

How To Forge Graphene In 3D Shape

The wonder material graphene gets many of its handy quirks from the fact that it exists in two dimensions, as a sheet of carbon only one atom thick. But to actually make use of it in practical applications, it usually needs to be converted into a 3D form. Now, researchers have developed a new and relatively simple way to do just that, using lasers to “forge” a three-dimensional pyramid out of graphene.

This isn’t the first time graphene has been given an extra dimension. In 2015, researchers from the University of Illinois molded graphene into 3D structures by layering it onto shaped substrates, and early this year MIT scientists found that tubes of the stuff could be shaped into 3D coral-like structures 10 times stronger than steel but just five percent as dense. Rice University researchers have also recently made graphene foam and reinforced it with carbon nanotubes.

But this new technique, developed by researchers in Finland and Taiwan, might be an easier and faster method to make 3D graphene. By focusing a laser onto a fine point on a 2D graphene lattice, the graphene at that spot is irradiated and bulges outwards. A variety of three-dimensional shapes can be made by writing patterns with the laser spot, with the height of the shape controlled by adjusting the irradiation dose at each particular point.

The team illustrated that technique by deforming a sheet of graphene into a 3D pyramid, standing 60 nm high. That sounds pretty tiny, but it’s 200 times taller than the graphene sheet itself.

We call this technique optical forging, since the process resembles forging metals into 3D shapes with a hammer,” says Mika Pettersson, co-author of the study. “In our case, a laser beam is the hammer that forges graphene into 3D shapes. The beauty of the technique is that it’s fast and easy to use; it doesn’t require any additional chemicals or processing. Despite the simplicity of the technique, we were very surprised initially when we observed that the laser beam induced such substantial changes on graphene. It took a while to understand what was happening.”

The researchers initially assumed that the laser had “doped” the graphene, introducing impurities into the material, but after further examination they found that wasn’t the case.

When we first examined the irradiated graphene, we were expecting to find traces of chemical species incorporated into the graphene, but we couldn’t find any,” comments Wei Yen Woon, co-author of the study. “After some more careful inspections, we concluded that it must be purely structural defects, rather than chemical doping, that are responsible for such dramatic changes on graphene.

The scientists explain that the optically forged graphene is structurally sound, highlighting its potential for building 3D architectures out of the material for a wide range of applications. In this form, the graphene has different electronic and optical properties from its 2D counterpart.

The research was published in the journal Nano Letters.

Source: Academy of Finland

The Ultra Smart Community Of The Future

Japan’s largest electronics show CEATEC – showcasing its version of our future – in a connected world with intelligent robots And cars that know when the driver is falling asleep. This is Omron‘s “Onboard Driving Monitoring Sensor,” checking its driver isn’t distracted.

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We are developing sensors that help the car judge what state the driver is in, with regards to driving. For example, if the driver has his eyes open and set on things he should be looking at, if the driver is distracted or looking at smartphones, and these types of situations,” explains Masaki Suwa, Omron Corp. Chief Technologist.

After 18 years of consumer electronics, CEATEC is changing focus to the Internet of Things and what it calls ‘the ultra-smart community of the future‘ A future where machines take on more important roles – machines like Panasonic‘s CaloRieco – pop in your plate and know exactly what you are about to consume.

By placing freshly cooked food inside the machine, you can measure total calories and the three main nutrients: protein, fat and carbohydrate. By using this machine, you can easily manage your diet,” says Panasonic staff engineer Ryota Sato.

Even playtime will see machines more involved – like Forpheus the ping playing robot – here taking on a Olympic bronze medalist – and learning with every stroke.
Rio Olympics Table Tennis player , Jun Mizutani, Bronze Medalist, reports: “It wasn’t any different from playing with a human being. The robot kept improving and getting better as we played, and to be honest, I wanted to play with it when it had reached its maximum level, to see how good it is.”

Graphene, Not Glass, Is The Key To Better Optics

A lens just a billionth of a metre thick could transform phone cameras. Researchers at Swinburne University in Melbourne, Australia, have created ultra-thin lenses that cap an optical fibre, and can produce images with the quality and sharpness of much larger glass lenses.

Compared with current lenses, our graphene lens only needs one film to achieve the same resolution,” says Professor Baohua Jia, a research leader at Swinburne’s Centre for Micro-Photonics. “In the future, mobile phones could be much thinner, without having to sacrifice the quality of their cameras. Our lens also allows infrared light to pass through, which glass lenses don’t.”

Producing graphene can be costly and challenging, so Baohua and her colleagues used a laser to pattern layers of graphene oxide (graphene combined with oxygen). By then removing the oxygen, they produced low-cost, patterned films of graphene, a thousand times thinner than a human hair. “By patterning the graphene oxide film in this way, its optical and electrical properties can be altered, which allowed us to place them in different devices,” she says.

Warm objects give off infrared light, so mobile phones with graphene lenses could be used to scan for hotspots in the human body and help in the early identification of diseases like breast cancer. By attaching the lens to a fibre optic tip, endoscopes — instruments that are currently several millimetres wide—could be made a million times smaller. The team is also investigating graphene’s amazing properties for their potential use as supercapacitors, capable of storing very large amounts of energy, which could replace conventional batteries.

Baohua’s work on graphene lenses was published in Nature Communications.

Source: https://cosmosmagazine.com/

Ancient Ink To Prevent Cancer Metastasis

For hundreds of years, Chinese calligraphers have used a plant-based ink to create beautiful messages and art. Now, a team of researchers from Fudan University (China)  reports in ACS Omega that this ink could noninvasively and effectively treat cancer cells that spread, or metastasize, to lymph nodes. Finding a simple and effective strategy to eliminate tumor metastatic lymph nodes is highly desired in clinical tumor treatment. Herein, we reported a Chinese traditional ink (Hu-ink)-based treatment for photothermal therapy (PTT) of tumor metastatic lymph nodes. By simple dilution, stable ink dispersion was obtained, which presents excellent photothermal effect because of its high absorption in near-infrared (NIR) region.

Meanwhile, as revealed by staining and photoacoustic imaging, Hu-ink could transfer to nearby lymph nodes after directly injected into the primary tumors. Under the guidance of dual-modality mapping, the metastatic sentinel lymph nodes could be subsequently eliminated by NIR irradiation.

 

The good biocompatibility of Hu-ink has also been verified by a series of experiments. Therefore, the Hu-ink-based treatment exhibits great potential for PTT of tumor metastatic lymph nodes in future clinical practice.

Source: http://pubs.acs.org/

Flying Electric Planes Between London And Paris

EasyJet could be flying planes powered by batteries rather than petroleum to destinations including Paris and Amsterdam within a decade. The UK carrier has formed a partnership with US firm Wright Electric, which is developing a battery-propelled aircraft for flights under two hoursEasyJet said the move would enable battery-powered aircraft to travel short-haul routes such as London to Paris and Amsterdam, and Edinburgh to Bristol. Wright Electric is aiming for an aircraft range of 335 miles, which would cover the journeys of about a fifth of passengers flown by easyJet.

Carolyn McCall, easyJet’s chief executive, said the aerospace industry would follow the lead of the automotive industry in developing electric engines that would cut emissions and noise.

For the first time in my career I can envisage a future without jet fuel and we are excited to be part of it,” she said. “It is now more a matter of when, not if, a short-haul electric plane will fly.”

The company said it was the next step in making the airline less harmful for the environment, after cutting carbon emissions per passenger kilometre by 31% between 2000 and 2016. Wright Electric claims that electric planes will be 50% quieter and 10% cheaper for airlines to buy and operate, with the cost saving potentially passed on to passengers. The US firm said its goal was for every short flight to be electric within 20 years. It has already built a two-seater prototype and is working towards a fully electric plane within a decade. The next step is to scale-up the technology to a 10-seater aircraft, and eventually to build a single aisle, short haul commercial plane, with the capacity to carry at least 120 passengers.

Source: https://www.theguardian.com/

Renewable Fuel From Water

Physicists at Lancaster University (in UK) are developing methods of creating renewable fuel from water using quantum technologyRenewable hydrogen can already be produced by photoelectrolysis where solar power is used to split water molecules into oxygen and hydrogen. But, despite significant research effort over the past four decades, fundamental problems remain before this can be adopted commercially due to inefficiency and lack of cost-effectivenessDr Manus Hayne  from the Department of Physics said: “For research to progress, innovation in both materials development and device design is clearly needed.

The Lancaster study, which formed part of the PhD research of Dr Sam Harrison, and is published in Scientific Reports, provides the basis for further experimental work into the solar production of hydrogen as a renewable fuel. It demonstrates that the novel use of nanostructures could increase the maximum photovoltage generated in a photoelectrochemical cell, increasing the productivity of splitting water molecules.

To the authors’ best knowledge, this system has never been investigated either theoretically or experimentally, and there is huge scope for further work to expand upon the results presented here,” said Dr Haynes. “Fossil-fuel combustion releases carbon dioxide into the atmosphere, causing global climate change, and there is only a finite amount of them available for extraction. We clearly need to transition to a renewable and low-greenhouse-gas energy infrastructure, and renewable hydrogen is expected to play an important role.

Fossil fuels accounted for almost 90% of energy consumption in 2015, with absolute demand still increasing due to a growing global population and increasing industrialisationPhotovoltaic solar cells are currently used to convert sunlight directly into electricity but solar hydrogen has the advantage that it is easily stored, so it can be used as and when needed. Hydrogen is also very flexible, making it highly advantageous  for remote communities. It can be converted to electricity in a fuel cell, or burnt in a boiler or cooker just like natural gas. It can even be used to fuel aircraft.

Source: http://www.lancaster.ac.uk/

Nanogels For Heart Attack Patients

Heart disease and heart-related illnesses are a leading cause of death around the world, but treatment options are limited. Now, one group reports in ACS Nano that encapsulating stem cells in a nanogel could help repair damage to the heart.

Myocardial infarction, also known as a heart attack, causes damage to the muscular walls of the heart. Scientists have tried different methods to repair this damage. For example, one method involves directly implanting stem cells in the heart wall, but the cells often don’t take hold, and sometimes they trigger an immune reaction. Another treatment option being explored is injectable hydrogels, substances that are composed of water and a polymer. Naturally occurring polymers such as keratin and collagen have been used but they are expensive, and their composition can vary between batches. So Ke Cheng, Hu Zhang, Jinying Zhang and colleagues wanted to see whether placing stem cells in inexpensive hydrogels with designed tiny pores that are made in the laboratory would work.

The team encapsulated stem cells in nanogels, which are initially liquid but then turn into a soft gel when at body temperature. The nanogel didn’t adversely affect stem cell growth or function, and the encased stem cells didn’t trigger a rejection response. When these enveloped cells were injected into mouse and pig hearts, the researchers observed increased cell retention and regeneration compared to directly injecting just the stem cells. In addition, the heart walls were strengthened. Finally, the group successfully tested the encapsulated stem cells in mouse and pig models of myocardial infarction.

Source: https://www.acs.org/
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Computer Reads Body Language

Researchers at Carnegie Mellon University‘s Robotics Institute have enabled a computer to understand body poses and movements of multiple people from video in real time — including, for the first time, the pose of each individual’s hands and fingers. This new method was developed with the help of the Panoptic Studio — a two-story dome embedded with 500 video cameras — and the insights gained from experiments in that facility now make it possible to detect the pose of a group of people using a single camera and a laptop computer.

Yaser Sheikh, associate professor of robotics, said these methods for tracking 2-D human form and motion open up new ways for people and machines to interact with each other and for people to use machines to better understand the world around them. The ability to recognize hand poses, for instance, will make it possible for people to interact with computers in new and more natural ways, such as communicating with computers simply by pointing at things.

Detecting the nuances of nonverbal communication between individuals will allow robots to serve in social spaces, allowing robots to perceive what people around them are doing, what moods they are in and whether they can be interrupted. A self-driving car could get an early warning that a pedestrian is about to step into the street by monitoring body language. Enabling machines to understand human behavior also could enable new approaches to behavioral diagnosis and rehabilitation, for conditions such as autism, dyslexia and depression.

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We communicate almost as much with the movement of our bodies as we do with our voice,” Sheikh said. “But computers are more or less blind to it.”

In sports analytics, real-time pose detection will make it possible for computers to track not only the position of each player on the field of play, as is now the case, but to know what players are doing with their arms, legs and heads at each point in time. The methods can be used for live events or applied to existing videos.

To encourage more research and applications, the researchers have released their computer code for both multi-person and hand pose estimation. It is being widely used by research groups, and more than 20 commercial groups, including automotive companies, have expressed interest in licensing the technology, Sheikh said.

Sheikh and his colleagues have presented reports on their multi-person and hand pose detection methods at CVPR 2017, the Computer Vision and Pattern Recognition Conference  in Honolulu.

Source: https://www.cmu.edu/

Biomaterial To Replace Plastics And Reduce Pollution

An inexpensive biomaterial that can be used to sustainably replace plastic barrier coatings in packaging and many other applications has been developed by Penn State researchers, who predict its adoption would greatly reduce pollution. Completely compostable, the material — a polysaccharide polyelectrolyte complex — is comprised of nearly equal parts of treated cellulose pulp from wood or cotton, and chitosan, which is derived from chitin — the primary ingredient in the exoskeletons of arthropods and crustaceans. The main source of chitin is the mountains of leftover shells from lobsters, crabs and shrimp consumed by humans.

These environmentally friendly barrier coatings have numerous applications ranging from water-resistant paper, to coatings for ceiling tiles and wallboard, to food coatings to seal in freshness, according to lead researcher Jeffrey Catchmark, professor of agricultural and biological engineering, College of Agricultural Sciences.

In the research, paperboard coated with the biomaterial exhibited strong oil and water barrier properties. The coating also resisted toluene, heptane and salt solutions and exhibited improved wet and dry mechanical and water vapor barrier properties.

The material’s unexpected strong, insoluble adhesive properties are useful for packaging as well as other applications, such as better performing, fully natural wood-fiber composites for construction and even flooring,” Jeffrey Catchmark said. “And the technology has the potential to be incorporated into foods to reduce fat uptake during frying and maintain crispness. Since the coating is essentially fiber-based, it is a means of adding fiber to diets.”

Source: http://news.psu.edu/

Nano Robots Build Molecules

Scientists at The University of Manchester have created the world’s first ‘molecular robot’ that is capable of performing basic tasks including building other molecules.

The tiny robots, which are a millionth of a millimetre in size, can be programmed to move and build molecular cargo, using a tiny robotic arm.

Each individual robot is capable of manipulating a single molecule and is made up of just 150 carbon, hydrogen, oxygen and nitrogen atoms. To put that size into context, a billion billion of these robots piled on top of each other would still only be the same size as a single grain of salt. The robots operate by carrying out chemical reactions in special solutions which can then be controlled and programmed by scientists to perform the basic tasks.

In the future such robots could be used for medical purposes, advanced manufacturing processes and even building molecular factories and assembly lines.

All matter is made up of atoms and these are the basic building blocks that form molecules. Our robot is literally a molecular robot constructed of atoms just like you can build a very simple robot out of Lego bricks, explains Professor David Leigh, who led the research at University’s School of Chemistry. “The robot then responds to a series of simple commands that are programmed with chemical inputs by a scientistIt is similar to the way robots are used on a car assembly line. Those robots pick up a panel and position it so that it can be riveted in the correct way to build the bodywork of a car. So, just like the robot in the factory, our molecular version can be programmed to position and rivet components in different ways to build different products, just on a much smaller scale at a molecular level.”

The research has been published in Nature.

Source: http://www.manchester.ac.uk/

New Treatment To Kill Cancer

Raise your hand if you haven’t been touched by cancer,” says Mylisa Parette to a roomful of strangers. Parette, the research manager for Keystone Nano (KN), has occasional opportunities to present her company’s technologies to business groups and wants to emphasize the scope of the problem that still confronts society. “It’s easier to see the effects of cancer when nobody raises their hand,” she says. Despite 40 years of the War on Cancer, one in two men and one in three women will be diagnosed with the disease at some point in their lifetime. Parette and her Keystone Nano colleagues are working on a new approach to cancer treatment. The company was formed from the collaboration of two Penn State faculty members who realized that the nanoparticle research that the one was undertaking could be used to solve the drug delivery problems that the other was facing.

Mark Kester, a pharmacologist at Penn State College of Medicine in Hershey, was working with a new drug that showed real promise as a cancer therapy but that could be dangerous if injected directly into the bloodstream. Jim Adair, a materials scientist in University Park, was creating nontoxic nanoparticles that could enclose drugs that might normally be toxic or hydrophobic and were small enough to be taken up by cells.

The two combined their efforts and, licensing the resulting technology from Penn State, they joined with entrepreneur Jeff Davidson, founder of the Biotechnology Institute and the Pennsylvania Biotechnology Association, to form Keystone Nano. The new company’s first hire was Parette, whose job is to translate the lab-scale technology into something that can be ramped up to an industrial scale, and to prepare that technology for FDA approval leading to clinical trials.

Davidson, Parette, and KN’s research team work out of the Zetachron building, a long, one-story science incubator a mile from Penn State’s University Park campus. Operated by the Centre County Industrial Development Corporation, the building was originally the home of the successful Penn State spin-out company that gave it its name. A second Keystone Nano lab was recently opened in the Hershey Center for Applied Research, a biotech incubator adjacent to Penn State College of Medicine.

Our excitement is that we think our technology has shown efficacy in a whole range of animal models,” Davidson, Keystone CEO, remarks during a recent meeting in the shared conference room at Zetachron. “We understand the method of action, the active ingredient. We think it has every chance of being useful in treating disease. Our question is, how do we push this forward from where we are today to determining, one way or another, that it really does work?

Keystone Nano is pioneering two approaches to cancer therapy, both of which rely on advances in nanotechnology to infiltrate tumors and deliver a therapeutic agent. The approach nearest to clinical trials is a ceramide nanoliposome, or what Davidson calls a “nano fat ball around an active ingredient.” Kester, in whose lab the approach was developed, thinks of it as a basketball with a thick bilayer coating that contains 30 percent active ceramide and a hollow interior that can hold another cancer drug.

Source: http://news.psu.edu/

Optical Computer

Researchers at the University of Sydney (Australia) have dramatically slowed digital information carried as light waves by transferring the data into sound waves in an integrated circuit, or microchipTransferring information from the optical to acoustic domain and back again inside a chip is critical for the development of photonic integrated circuits: microchips that use light instead of electrons to manage data.

These chips are being developed for use in telecommunications, optical fibre networks and cloud computing data centers where traditional electronic devices are susceptible to electromagnetic interference, produce too much heat or use too much energy.

The information in our chip in acoustic form travels at a velocity five orders of magnitude slower than in the optical domain,” said Dr Birgit Stiller, research fellow at the University of Sydney and supervisor of the project.

It is like the difference between thunder and lightning,” she said.

This delay allows for the data to be briefly stored and managed inside the chip for processing, retrieval and further transmission as light wavesLight is an excellent carrier of information and is useful for taking data over long distances between continents through fibre-optic cables.

But this speed advantage can become a nuisance when information is being processed in computers and telecommunication systems.

Source: https://sydney.universty.au/

Skin Patches Melt Fat

Researchers have devised a medicated skin patch that can turn energy-storing white fat into energy-burning brown fat locally while raising the body’s overall metabolism. The patch could be used to burn off pockets of unwanted fat such as “love handles” and treat metabolic disorders, such as obesity and diabetes, according to researchers at Columbia University Medical Center (CUMC) and the University of North Carolina. Humans have two types of fat. White fat stores excess energy in large triglyceride droplets. Brown fat has smaller droplets and a high number of mitochondria that burn fat to produce heat. Newborns have a relative abundance of brown fat, which protects against exposure to cold temperatures. But by adulthood, most brown fat is lost.

For years, researchers have been searching for therapies that can transform an adult’s white fat into brown fat—a process named browning—which can happen naturally when the body is exposed to cold temperatures—as a treatment for obesity and diabetes.

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There are several clinically available drugs that promote browning, but all must be given as pills or injections,” said study co-leader Li Qiang, PhD, assistant professor of pathology & cell biology at Columbia. “This exposes the whole body to the drugs, which can lead to side effects such as stomach upset, weight gain, and bone fractures. Our skin patch appears to alleviate these complications by delivering most drugs directly to fat tissue.

To apply the treatment, the drugs are first encased in nanoparticles, each roughly 250 nanometers (nm) in diameter—too small to be seen by the naked eye. (In comparison, a human hair is about 100,000 nm wide.) The nanoparticles are then loaded into a centimeter-square skin patch containing dozens of microscopic needles. When applied to skin, the needles painlessly pierce the skin and gradually release the drug from nanoparticles into underlying tissue.

The findings, from experiments in mice, were published online today in ACS Nano.

Source: http://newsroom.cumc.columbia.edu/

Very Fast Magnetic Data Storage

For almost seventy years now, magnetic tapes and hard disks have been used for data storage in computers. In spite of many new technologies that have been developed in the meantime, the controlled magnetization of a data storage medium remains the first choice for archiving information because of its longevity and low price. As a means of realizing random access memories (RAMs), however, which are used as the main memory for processing data in computers, magnetic storage technologies were long considered inadequate. That is mainly due to its low writing speed and relatively high energy consumption.

In 1956, IBM introduced the first magnetic hard disc, the RAMAC. ETH researchers have now tested a novel magnetic writing technology that could soon be used in the main memories of modern computers

Pietro Gambardella, Professor at the Department of Materials of the Eidgenössische Technische Hochschule Zürich (ETHZ, Switzerland), and his colleagues, together with colleagues at the Physics Department and at the Paul Scherrer Institute (PSI), have now shown that using a novel technique, magnetic storage can still be achieved very fast and without wasting energy.

In 2011, Gambardella and his colleagues already demonstrated a technique that could do just that: An electric current passing through a specially coated semiconductor film inverted the magnetization in a tiny metal dot. This is made possible by a physical effect called spin-orbit-torque. In this effect, a current flowing in a conductor leads to an accumulation of electrons with opposite magnetic moment (spins) at the edges of the conductor. The electron spins, in turn, create a magnetic field that causes the atoms in a nearby magnetic material to change the orientation of their magnetic moments. In a new study the scientists have now investigated how this process works in detail and how fast it is.

The results were recently published in the scientific journal Nature Nanotechnology.

Source: https://www.ethz.ch/

Robots With The Sense Of Touch

A team of researchers from the University of Houston (UH) has reported a breakthrough in stretchable electronics that can serve as an artificial skin, allowing a robotic hand to sense the difference between hot and cold, while also offering advantages for a wide range of biomedical devices.

Cunjiang Yu, Bill D. Cook Assistant Professor of mechanical engineering and lead author for the paper, said the work is the first to create a semiconductor in a rubber composite format, designed to allow the electronic components to retain functionality even after the material is stretched by 50 percent. The semiconductor in rubber composite format enables stretchability without any special mechanical structure. Yu noted that traditional semiconductors are brittle and using them in otherwise stretchable materials has required a complicated system of mechanical accommodations. “That’s both more complex and less stable than the new discovery, as well as more expensive.”

Our strategy has advantages for simple fabrication, scalable manufacturing, high-density integration, large strain tolerance and low cost,” he said.

Yu and the rest of the team – co-authors include first author Hae-Jin Kim, Kyoseung Sim and Anish Thukral, all with the UH Cullen College of Engineering – created the electronic skin and used it to demonstrate that a robotic hand could sense the temperature of hot and iced water in a cup. The skin also was able to interpret computer signals sent to the hand and reproduce the signals as .

The robotic skin can translate the gesture to readable letters that a person like me can understand and read,” Yu said.

The work is reported in the journal Science Advances.

Source: http://www.uh.edu/

Magnetic Cellular ‘Legos’ For Tissue Engineering

By incorporating magnetic nanoparticles in cells and developing a system using miniaturized magnets, researchers from 3 associated universities* in Paris (France) , have succeeded in creating cellular magneticLegos.” They were able to aggregate cells using only magnets and without an external supporting matrix, with the cells then forming a tissue that can be deformed at will. This approach, which is detailed in Nature Communications, could prove to be a powerful tool for biophysical studies, as well as the regenerative medicine of tomorrow.

Nanotechnology has quickly swept across the medical field by proposing sometimes unprecedented solutions at the furthest limits of current treatments, thereby becoming central to diagnosis and therapy, notably for the regeneration of tissue. A current challenge for regenerative medicine is to create a cohesive and organized cellular assembly without using an external supporting matrix. This is a particularly substantial challenge when it involves synthesizing thick and/or large-sized tissue, or when these tissues must be stimulated like their in vivo counterparts (such as cardiac tissue or cartilage) in order to improve their functionality.

The researchers met this challenge by using magnetism to act on the cells at a distance, in order to assemble, organize, and stimulate them. Cells, which are the building blocks of tissue, are thus magnetized in advance through the incorporation of magnetic nanoparticles, thus becoming true cellular magnetic “Legos” that can be moved and stacked using external magnets. In this new system acting as a magnetic tissue stretcher, the magnetized cells are trapped on a first micromagnet, before a second, mobile magnet traps the aggregate formed by the cells. The movement of the two magnets can stretch or compress the resulting tissue at will.

Researchers first used embryonic stem cells to test their system. They began by showing that the incorporation of nanoparticles had no impact on either the functioning of the stem cell or its capacity for differentiation. These functional magnetic stem cells were then tested in the stretcher, in which they remarkably differentiated toward cardiac cell precursors when stimulation imposed “magnetic beating” imitating the contraction of the heart. These results demonstrate the role that purely mechanical factors can play in cell differentiation.

This “all-in-one” approach, which makes it possible to build and manipulate tissue within the same system, could thus prove to be a powerful tool both for biophysical studies and tissue engineering.

* Laboratoire Matière et Systèmes Complexes (CNRS/Université Paris Diderot), in collaboration with the Laboratoire Adaptation Biologique et Vieillissement (CNRS/UPMC) and the Centre de Recherche Cardiovasculaire de Paris (Inserm/Université Paris Descartes)

Source: https://www.nature.com/
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Rapid, Cheap Liver Cancer Test

University of Utah researchers say they are designing a diagnostic method that will be able to accurately identify signs of liver cancer within minutes, saving critical time for patients of the stealthy disease. The new type of test could forever change how people screen for the disease, said Marc Porter, a U. chemical engineering and chemistry professor who is leading the research along with Dr. Courtney Scaife, a surgeon who both practices and teaches surgery for the university. Porter said the long-term vision is for the tool itself to become as automatic and portable as a pregnancy test, though additional technology — called a spectrometer — is currently needed to precisely measure the results of the test.

A small domino-sized cartridge holds a membrane for a new field test for liver cancer developed by researchers from the University of Utah. The test doesn’t involve sending a specimen to a blood lab and cuts the wait time for results from two weeks to two minutes. It can be administered wherever the patient is, which will be valuable for developing nations with little access to hospitals.

It’s really compact, it’s simple and low cost,” he said of the test kit.

Liver cancer is difficult to survive because typically it is highly developed by the time symptoms show up, Porter said. It is the second deadliest form of cancer worldwide, resulting in about 788,000 deaths in 2015, according to the World Health Organization. “All too often, the cancer is diagnosed past when you can actually have surgical intervention,” Porter said.

Currently, a blood test taken to determine the presence of liver cancer is usually sent to a lab offsite, where it takes days or even up to two weeks to test and return, said Vincent Horiuchi, spokesman for the U.’s College of Engineering. Those days are precious time that is lost in the fight against the disease, he said.

Source: https://unews.utah.edu/

How To Draw Electricity from the Bloodstream

Men build dams and huge turbines to turn the energy of waterfalls and tides into electricity. To produce hydropower on a much smaller scale, Chinese scientists have now developed a lightweight power generator based on carbon nanotube fibers suitable to convert even the energy of flowing blood in blood vessels into electricity.

For thousands of years, people have used the energy of flowing or falling water for their purposes, first to power mechanical engines such as watermills, then to generate electricity by exploiting height differences in the landscape or sea tides. Using naturally flowing water as a sustainable power source has the advantage that there are (almost) no dependencies on weather or daylight. Even flexible, minute power generators that make use of the flow of biological fluids are conceivable. How such a system could work is explained by a research team from Fudan University in Shanghai, China. Huisheng Peng and his co-workers have developed a fiber with a thickness of less than a millimeter that generates electrical power when surrounded by flowing saline solution—in a thin tube or even in a blood vessel.

The construction principle of the fiber is quite simple. An ordered array of carbon nanotubes was continuously wrapped around a polymeric core. Carbon nanotubes are well known to be electroactive and mechanically stable; they can be spun and aligned in sheets. In the as-prepared electroactive threads, the carbon nanotube sheets coated the fiber core with a thickness of less than half a micron. For power generation, the thread or “fiber-shaped fluidic nanogenerator” (FFNG), as the authors call it, was connected to electrodes and immersed into flowing water or simply repeatedly dipped into a saline solution. “The electricity was derived from the relative movement between the FFNG and the solution,” the scientists explained. According to the theory, an electrical double layer is created around the fiber, and then the flowing solution distorts the symmetrical charge distribution, generating an electricity gradient along the long axis.

The power output efficiency of this system was high. Compared with other types of miniature energy-harvesting devices, the FFNG was reported to show a superior power conversion efficiency of more than 20%. Other advantages are elasticity, tunability, lightweight, and one-dimensionality, thus offering prospects of exciting technological applications. The FFNG can be made stretchable just by spinning the sheets around an elastic fiber substrate. If woven into fabrics, wearable electronics become thus a very interesting option for FFNG application. Another exciting application is the harvesting of electrical energy from the bloodstream for medical applications. First tests with frog nerves proved to be successful.

The findings are published in  the journal Angewandte Chemie.

Source: http://newsroom.wiley.com/

Big Data And Skyrmions

Today’s world, rapidly changing because of “big data”, is encapsulated in trillions of tiny magnetic objects magnetic bits – each of which stores one bit of data in magnetic disk drives.   A group of scientists from the Max Planck Institutes in Halle and Dresden have discovered a new kind of magnetic nano-object in a novel material that could serve as a magnetic bit with cloaking properties to make a magnetic disk drive with no moving parts – a Racetrack Memory – a reality in the near future.

Most digital data is stored in the cloud as magnetic bits within massive numbers of magnetic disk drives.  Over the past several decades these magnetic bits have shrunk by many orders of magnitude, reaching limits where the boundaries of these magnetic regions can have special properties.  In some special materials these boundaries – “magnetic domain walls” – can be described as being topological. What this means is that these walls can be thought of as having a special magical cloak – what is referred to by scientists as “topological protection”.   An important consequence is that such magnetic walls are more stable to perturbations than similar magnetic bits without topological protection that are formed in conventional magnetic materials.  Thus, these “topological magnetic objects could be especially useful for storing1”s and “0”s, the basic elements of digital data.   One such object is a “magnetic skyrmion” which is a tiny magnetic region, perhaps tens to hundreds of atoms wide, separated from a surrounding magnetic region by a chiral domain wall.  Until recently only one type of skyrmion has been found in which it is surrounded by a chiral domain wall that takes the same form in all directions.   But there have been predictions of several other types of skyrmions that were not yet observed.

Now in a paper published in Nature, scientists from Prof. Stuart Parkin’s NISE department at the Max Planck Institute for Microstructure Physics in Halle, Germany, have found a second class of skyrmions, what are called “anti-skyrmions”, in materials synthesized in Prof. Claudia Felser.   The scientists from Halle and Dresden have found these tiny magnetic objects in a special class of versatile magnetic compounds called Heusler compounds.   Of these Heusler compounds, a tiny subset have just the right crystal symmetry to allow for the possibility of forming anti-skyrmions but not skyrmions.

The special cloaking properties of skyrmions makes them of great interest for a radically new form of solid-state memorythe Racetrack Memory. In Racetrack Memory digital data is encoded within magnetic domain walls that are packed closely within nanoscopic magnetic wires.  One of the unique features of Racetrack Memory, which is distinct from all other memories, is that the walls are moved around the nanowires themselves using recent discoveries in spin-orbitronics domain walls.  Very short pulses of current move all the backwards and forwards along the nano-wires. The walls – the magnetic bits – can be read and written by devices incorporated directly into the nanowires themselves, thereby eliminating any mechanical parts.

Source: https://www.cpfs.mpg.de/

Urban Farming At Home

Growing your own vegetables and herbs can be a laborious process. Lack of space in urban environments makes it even harder. But this smart garden is bringing the window box into the modern age. Much like Nespresso coffee capsules, users ‘plant’ this soil pod… containing the seeds and all the nutrients which are released in sync with the plant’s life cycle.

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This is the plastic container they put the growing substrate in here. It has a wick solution, so basically it starts to drain the water from the water tank, and the lamp does the rest of the job. The lamp imitates daylight time, so it’s 16 hours on and 8 hours off. So far we have tested some 7,000 different plants and each growing substrate is designed specifically for this plant,” says Karel Kask, sales Manager, Click and Grow. Estonia-based ‘Click and Grow‘ says it’s tested up to a thousand lighting solutions to ensure optimal growth. The red and white lights deliver the perfect spectrum they say, speeding up growth by 30 to 50 percent, depending on the plant. Each soil pod provides up to 3 harvests. ‘Click and Grow‘ was inspired by NASA technology used to grow food in space. Here, astronauts aboard the International Space Station sample lettuce they’ve grown.

They’re using quite similar soil-based solutions; so they take the soil substrate into space and grow them already in there. They have an automated watering solution. So it’s quite similar to the solution that we do.The Smart Garden 9, its latest and most advanced model, was displayed at this week’s IFA tech fair in Berlin,” adds Kask.

More Durable Fuel Cells For Hydrogen Electric Car

Take a ride on the University of Delaware’s (UDFuel Cell bus, and you see that fuel cells can power vehicles in an eco-friendly way. In just the last two years, Toyota, BMW and Honda have released vehicles that run on fuel cells, and carmakers such as GM, BMW and VW are working on prototypes.  If their power sources lasted longer and cost less, fuel cell vehicles could go mainstream faster. Now, a team of engineers at UD has developed a technology that could make fuel cells cheaper and more durable.

Hydrogen-powered fuel cells are a green alternative to internal combustion engines because they produce power through electrochemical reactions, leaving no pollution behind. Materials called catalysts spur these electrochemical reactions. Platinum is the most common catalyst in the type of fuel cells used in vehicles. However, platinum is expensive — as anyone who’s shopped for jewelry knows. The metal costs around $30,000 per kilogram. Instead, the UD team made a catalyst of tungsten carbide, which goes for around $150 per kilogram. They produced tungsten carbide nanoparticles in a novel way, much smaller and more scalable than previous methods.

The material is typically made at very high temperatures, about 1,500 Celsius, and at these temperatures, it grows big and has little surface area for chemistry to take place on,” explains Vlachos, professor at the Catalysis Center for Energy Innovation (UD). “Our approach is one of the first to make nanoscale material of high surface area that can be commercially relevant for catalysis.”

The researchers made tungsten carbide nanoparticles using a series of steps including hydrothermal treatment, separation, reduction, carburization and more. The results are described in a paper published in Nature Communications.

Source: https://www.udel.edu/

China, Global Leader In NanoScience

Mobile phones, computers, cosmetics, bicyclesnanoscience is hiding in so many everyday items, wielding a huge influence on our lives at a microscale level. Scientists and engineers from around the world exchanged new findings and perceptions on nanotechnology at the recent 7th International Conference on Nanoscience and Technology (ChinaNANO 2017) in Beijing last week. China has become a nanotechnology powerhouse, according to a report released at the conference. China’s applied nanoscience research and the industrialization of nanotechnology have been developing steadily, with the number of nano-related patent applications ranking among the top in the world.

According to Bai Chunli, president of the Chinese Academy of Sciences (CAS), China faces new opportunities for nanoscience research and development as it builds the National Center for Nanoscience and Technology  (NCNST) and globally influential national science centers.

We will strengthen the strategic landscape and top-down design for developing nanoscience, which will contribute greatly to the country’s economy and society,” said Bai.

Nanoscience can be defined as the study of the interaction, composition, properties and manufacturing methods of materials at a nanometer scale. At such tiny scales, the physical, chemical and biological properties of materials are different from those at larger scales — often profoundly so.

For example, alloys that are weak or brittle become strong and ductile; compounds that are chemically inert become powerful catalysts. It is estimated that there are more than 1,600 nanotechnology-based consumer products on the market, including lightweight but sturdy tennis rackets, bicycles, suitcases, automobile parts and rechargeable batteries. Nanomaterials are used in hairdryers or straighteners to make them lighter and more durable. The secret of how sunscreens protect skin from sunburn lies in the nanometer-scale titanium dioxide or zinc oxide they contain.

In 2016, the world’s first one-nanometer transistor was created. It was made from carbon nanotubes and molybdenum disulphide, rather than silicon.
Carbon nanotubes or silver nanowires enable touch screens on computers and televisions to be flexible, said Zhu Xing, chief scientist (CNST). Nanotechnology is also having an increasing impact on healthcare, with progress in drug delivery, biomaterials, imaging, diagnostics, active implants and other therapeutic applications. The biggest current concern is the health threats of nanoparticles, which can easily enter body via airways or skin. Construction workers exposed to nanopollutants face increased health risks.

The report was co-produced by Springer Nature, National Center for Nanoscience and Technology (NCNST) and the National Science Library of the Chinese Academy of Sciences (CAS).

Source: http://www.shanghaidaily.com/

Regular Hydrogen Electric Bus Lines Will Open In 2019

Koningshooikt – Van Hool, the independent Belgian bus, coach and industrial vehicle manufacturer has won a contract in Pau, France, to supply 8 Exqui.Cities, known as “tram-buses“, powered by hydrogen. The use of hydrogen buses is not only a first for France it is also a world first for a full BRT (Bus Rapid Transit) system with 18-metre-long articulated tram-buses. This is the first time that hydrogen technology has been integrated as a power source in a tram-bus.

The brand new vehicle is an 18.62 metre-long articulated tram-bus with a 125 passenger capacity and an autonomy of around 300 km. The order of 8 Exqui.Cities will be delivered to the SMTU-PPP (Syndicat Mixte de Transports urbains – Pau Portes des Pyrénées) and the STAP (Société de Transport de l’Agglomération Paloise) in the second half of 2019.

The bus’s power source is an electric hybrid. On the one hand hydrogen (H2) and oxygen (O2) are converted to electricity in the fuel cell using electrolysis in “real time” and, on the other hand, the lithium batteries and electric motors provide additional power wherever and whenever it is needed. The energy that is released when the vehicle’s brakes are applied is also re-used. The use of this technology results in the 0-emission of greenhouse gases or air polluting substances. The vehicle’s only emission is water vapour.

Additional advantages offered by hydrogen buses include their autonomy of over three hundred kilometres and fast re-fuelling (10 minutes). These buses therefore allow bus companies to reach the highest level of operational flexibility and productivity.

Source: http://www.vanhool.be/

Electric Car: More Silicon To Enhance Batteries

Silicon – the second most abundant element in the earth’s crust – shows great promise in Li-ion batteries, according to new research from the University of Eastern Finland. By replacing graphite anodes with silicon, it is possible to quadruple anode capacity.

In a climate-neutral society, renewable and emission-free sources of energy, such as wind and solar power, will become increasingly widespread. The supply of energy from these sources, however, is intermittent, and technological solutions are needed to safeguard the availability of energy also when it’s not sunny or windy. Furthermore, the transition to emission-free energy forms in transportation requires specific solutions for energy storage, and lithium-ion batteries are considered to have the best potential.

Researchers from the University of Eastern Finland introduced new technology to Li-ion batteries by replacing graphite used in anodes by silicon. The study analysed the suitability of electrochemically produced nanoporous silicon for Li-ion batteries. It is generally understood that in order for silicon to work in batteries, nanoparticles are required, and this brings its own challenges to the production, price and safety of the material. However, one of the main findings of the study was that particles sized between 10 and 20 micrometres and with the right porosity were in fact the most suitable ones to be used in batteries. The discovery is significant, as micrometre-sized particles are easier and safer to process than nanoparticles. This is also important from the viewpoint of battery material recyclability, among other things.

In our research, we were able to combine the best of nano– and micro-technologies: nano-level functionality combined with micro-level processability, and all this without compromising performance,” Researcher Timo Ikonen from the University of Eastern Finland says. “Small amounts of silicon are already used in Tesla’s batteries to increase their energy density, but it’s very challenging to further increase the amount,” he continues.

Next, researchers will combine silicon with small amounts of carbon nanotubes in order to further enhance the electrical conductivity and mechanical durability of the material.

The findings were published in Scientific Reports .

Source: http://news.cision.com/

How To Convert 90% Of Water Into Hydrogen

Researchers from North Carolina State University (NC State) have significantly boosted the efficiency of two techniques, for splitting water to create hydrogen gas and splitting carbon dioxide (CO2) to create carbon monoxide (CO). The products are valuable feedstock for clean energy and chemical manufacturing applications. The water-splitting process successfully converts 90 percent of water into hydrogen gas, while the CO2-splitting process converts more than 98 percent of the CO2 into CO. In addition, the process also uses the resulting oxygen to convert methane into syngas, which is itself a feedstock used to make fuels and other products.


These advances are made possible by materials that we specifically designed to have the desired thermodynamic properties for each process,” says Fanxing Li, an associate professor of chemical and biomolecular engineering at NC State who is corresponding author of two papers on the work. “These properties had not been reported before unless you used rare earth materials.”

For the CO2-splitting process, researchers developed a nanocomposite of strontium ferrite dispersed in a chemically inert matrix of calcium oxide or manganese oxide. As CO2 is run over a packed bed of particles composed of the nanocomposite, the nanocomposite material splits the CO2 and captures one of the oxygen atoms. This reduces the CO2, leaving only CO behind.

Previous CO2 conversion techniques have not been very efficient, converting well below 90 percent of the CO2 into CO,” Li says. “We reached conversion rates as high as 99 percent. “And CO is valuable because it can be used to make a variety of chemical products, including everything from polymers to acetic acid,” Li adds.

Meanwhile, the oxygen captured during the CO2-splitting process is combined with methane and converted into syngas using solar energy.

Source: https://news.ncsu.edu/

How To Store Data At The Molecular Level

From smartphones to nanocomputers or supercomputers, the growing need for smaller and more energy efficient devices has made higher density data storage one of the most important technological quests. Now scientists at the University of Manchester have proved that storing data with a class of molecules known as single-molecule magnets is more feasible than previously thought. The research, led by Dr David Mills and Dr Nicholas Chilton, from the School of Chemistry, is being published in Nature. It shows that magnetic hysteresis, a memory effect that is a prerequisite of any data storage, is possible in individual molecules at -213 °C. This is tantalisingly close to the temperature of liquid nitrogen (-196 °C).

The result means that data storage with single molecules could become a reality because the data servers could be cooled using relatively cheap liquid nitrogen at -196°C instead of far more expensive liquid helium (-269 °C). The research provides proof-of-concept that such technologies could be achievable in the near future.

The potential for molecular data storage is huge. To put it into a consumer context, molecular technologies could store more than 200 terabits of data per square inch – that’s 25,000 GB of information stored in something approximately the size of a 50p coin, compared to Apple’s latest iPhone 7 with a maximum storage of 256 GB.

Single-molecule magnets display a magnetic memory effect that is a requirement of any data storage and molecules containing lanthanide atoms have exhibited this phenomenon at the highest temperatures to date. Lanthanides are rare earth metals used in all forms of everyday electronic devices such as smartphones, tablets and laptops. The team achieved their results using the lanthanide element dysprosium.

This is very exciting as magnetic hysteresis in single molecules implies the ability for binary data storage. Using single molecules for data storage could theoretically give 100 times higher data density than current technologies. Here we are approaching the temperature of liquid nitrogen, which would mean data storage in single molecules becomes much more viable from an economic point of view,’ explains Dr Chilton.

The practical applications of molecular-level data storage could lead to much smaller hard drives that require less energy, meaning data centres across the globe could become a lot more energy efficient.

Source: http://www.manchester.ac.uk/

Canakinumab Drug Lowers Risk Of Fatal Lung Cancer By 75%

It turns out that cholesterol isn’t the only thing you have to worry about to keep your heart healthy. In recent years, doctors have started to focus on inflammation — the same process that makes cuts red and painful — as an important contributor to a heart attack. It’s the reason doctors recommend low-dose aspirin to prevent recurrent heart attacks in people who have already had them, why they also prescribe statins, which lower both cholesterol and inflammation, and why they have started to measure inflammation levels in the blood.

But it’s never been clear exactly how much inflammation adds to heart disease risk. Since statins lower both, it’s hard to tell whether inflammation or cholesterol has the bigger impact on heart problems. But in a new paper published in the New England Journal of Medicine and presented at the European Society of Cardiology meeting, scientists say they now have proof that lowering inflammation alone, without affecting cholesterol, also reduces the risk of a heart attack.

In the study, 10,000 people who have already had a heart attack were randomly assigned to get injected with a placebo or different doses of a drug called canakinumab. Canakinumab, made by Novartis, is currently approved to treat rare immune-related conditions and works to reduce inflammation but does not affect cholesterol levels. After four years, the people who received the drug had a 15% lower chance of having a heart attack or stroke compared to people who didn’t get the drug. The medication also reduced the need for angioplasty or bypass surgery by 30%.

Even I am pinching myself,” says Dr. Paul Ridker, who led the study and is director of the center for cardiovascular disease prevention at Brigham and Women’s Hospital and is a pioneer in exposing the role inflammation plays in heart disease. “This outcome is more than we hoped for. The bottom line is we now have clear evidence that lowering inflammation through this pathway lowers rates of heart attack and stroke with no change at all in cholesterol.”

Perhaps more intriguing are additional results that Ridker reported, related to cancer. In a separate study published in the Lancet using data from the same study, he found that people taking canakinumab lowered their risk of dying from any cancer over four years by 50%, and their risk of fatal lung cancer by 75%.

Source: http://time.com/

No More Visit To The Doctor’s Office

A visit to the doctor’s office can feel like the worst thing when you’re already sick. This small device is aimed at replacing physical face-to-face check ups. It’s made by Israel’s Tytocare, a leading telemedicine company. Their Tyto device allows patients to conduct examinations of organs and be diagnosed by remote clinicians.

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We basically replicate a face-to-face interaction with a remote clinician while allowing him to do a full physical examination, analysis and the diagnosis of a patient at home,” said Dedi Gilad, CEO of Tytocare.

The associated TytoApp guides users through complicated examinations. It can be used to check heart rate or temperature — as well as conduct examinations of the ears, throat and lungs. And it allows a clinician to interact with patients online or offline. It also represents a significant cost saving – in the US a basic primary care visit costs around 170 dollars, three times the cost of telemedicine appointments. The system was tested at Israel’s Schneider children’s hospital.

What we found was really remarkable, that there was almost no difference between the two types of examinations…But we must be careful about the use. There are certain diseases, certain complaints, that can not be answered by this kind of device and we should carefully judge case by case and be aware of the limitations of this device,”  explains Prof. Yehezkel Waisman, Director of The Emergency Medicine department at Schneider children hospital.

Telemedecine does have its critics, who believe that real-time encounters with a doctor will always be superior. But those behind it say it could drastically cut the number of face-to-face doctors’ visits and save money for healthcare providers and insurers.

Source: http://www.tytocare.com/
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http://www.reuters.com/

Nano-based Yarns Generate Electricity

An international research team led by scientists at The University of Texas at Dallas and Hanyang University in South Korea has developed high-tech yarns that generate electricity when they are stretched or twisted.

In a study published in the journal Science, researchers describe “twistronyarns and their possible applications, such as harvesting energy from the motion of ocean waves or from temperature fluctuations. When sewn into a shirt, these yarns served as a self-powered breathing monitor.

The easiest way to think of twistron harvesters is, you have a piece of yarn, you stretch it, and out comes electricity,” said Dr. Carter Haines BS’11, PhD’15, associate research professor in the Alan G. MacDiarmid NanoTech Institute at UT Dallas and co-lead author of the article. The article also includes researchers from South Korea, Virginia Tech, Wright-Patterson Air Force Base and China.

Coiled carbon nanotube yarns, created at The University of Texas at Dallas and imaged here with a scanning electron microscope, generate electrical energy when stretched or twisted.
The yarns are constructed from carbon nanotubes, which are hollow cylinders of carbon 10,000 times smaller in diameter than a human hair. The researchers first twist-spun the nanotubes into high-strength, lightweight yarns. To make the yarns highly elastic, they introduced so much twist that the yarns coiled like an over-twisted rubber band.

In order to generate electricity, the yarns must be either submerged in or coated with an ionically conducting material, or electrolyte, which can be as simple as a mixture of ordinary table salt and water.

Fundamentally, these yarns are supercapacitors,” said Dr. Na Li, a research scientist at the NanoTech Institute and co-lead author of the study. “In a normal capacitor, you use energy — like from a battery — to add charges to the capacitor. But in our case, when you insert the carbon nanotube yarn into an electrolyte bath, the yarns are charged by the electrolyte itself. No external battery, or voltage, is needed.

When a harvester yarn is twisted or stretched, the volume of the carbon nanotube yarn decreases, bringing the electric charges on the yarn closer together and increasing their energy, Haines said. This increases the voltage associated with the charge stored in the yarn, enabling the harvesting of electricity.

Source: http://www.utdallas.edu/

How To Keep Warm In Extreme Cold Weather

Some of the winter weather gear worn by the US Army was designed 30 years ago. It’s heavy and can cause overheating during exertion, while also not doing a very good job of keeping the extremities from going numb.

 

That’s problematic if soldiers have to operate weapons as soon as they land,” said Paola D’Angelo, a research bioengineer at the US Army’s Natick Soldier Research, Development and Engineering Center in Massachusetts. “So we want to pursue this fundamental research to see if we can modify hand wear for that extreme cold weather.”

Scientists are developing smart fabrics that heat up when powered and can capture sweat. The work, which was presented at the 254th National Meeting and Exposition of the American Chemical Society, is based on research from Stanford University in California. A team embedded a network of very fine silver nanowires in cotton, and was able to heat the fabric by applying power to the wires. D’Angelo and her colleagues are working to extend the approach to other fabrics more suitable for military uniforms, including polyester and a cotton/nylon blend. By applying three volts – the output of a typical watch battery – to a one-inch square of fabric, they were able to raise its temperature by almost 40 degrees C. The researchers are also incorporating a layer of hydrogel particles made of polyethylene glycol that will absorb sweat and stop the other layers of the fabric from getting wet.

Once we have optimised the coating, we can start looking at scaling up,” said D’Angelo. The fabric has been tested with up to three washes and still works the same as unwashed fabric for most of the textiles being tested.

Source: http://www.imeche.org/

Three-Wheeled Electric Vehicle

This three-wheeled vehicle is the culmination of 10 years of work For Mark Frohnmayer. It’s the Arcimoto SRK — an all-electric commuter vehicle retailing at a base price of $12,000 — and Frohnmayer hopes his first customers will have them in their driveways by the end of summer.

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“I thought, you know, if we can build something that was much closer to the motorcycle in terms of efficiency and fun factor and, you know, footprint on the road but was close to the car in terms of capabilities and enclosable and carries groceries and stable, that we’d have a real product opportunity that the world has been missing for a long time,” says Mark Frohnmayer, Founder and President of Arcimoto SRK.

Frohnmayer built seven generations of prototypes with regular car steering wheels. His breakthrough moment came when he replaced the steering wheel with motorcycle handlebars.

By switching to handlebar steering, we were able to move the passengers into a more upright seating position like you’d have on a city scooter and that let us shorten the vehicle by almost two feet and drop hundreds of pounds — almost 600 pounds — of weight between generations 6 or generation 7 and generation 8 and that moved us way beyond our actual weight target and let us drop the cost to a point where it was actually going to be in the sweet spot that we were aiming for”, explains Frohnmayer.

The SRK can reach 85 mph (137 km/h) and has a range of 70 miles (113 km). It has an equivalent fuel consumption of 230 MPG”, the company says.
Arcimoto has already taken 1,500 reservations and hopes it’s just the beginning. Frohnmayer believes his small cars will soon have a big impact in the fight against climate change – offering commuters a sustainable and eco-friendly option to get to work.

Source: https://www.arcimoto.com/

How To Detect, Kill Circulating Tumor Cells

A nanolaser known as the spaser can serve as a super-bright, water-soluble, biocompatible probe capable of finding metastasized cancer cells in the blood stream and then killing these cells, according to a new research study. The spaser can be used as an optical probe and when released into the body (possibly through an injection or drinking a solution), it can find and go after circulating tumor cells (CTCs), stick to them and destroy these cells by breaking them apart to prevent cancer metastases. The spaser absorbs laser light, heats up, causes shock waves in the cell and destroys the cell membrane.

The spaser, which stands for surface plasmon amplification by stimulated emission of radiation, is a nanoparticle, about 20 nanometers in size or hundreds times smaller than human cells. It has folic acid attached to its surface, which allows selective molecular targeting of cancer cells. The folate receptor is commonly overexpressed on the surface of most human cancer cells and is weakly expressed in normal cells. The discovery was made by researchers at Georgia State University, the University of Arkansas for Medical Sciences, the University of Arkansas at Little Rock and the Siberian Branch of the Russian Academy of Science.

There is no other method to reliably detect and destroy CTCs,” said Dr. Mark Stockman, director of the Center for Nano-Optics and professor of physics at Georgia State. “This is the first. This biocompatible spaser can go after these cells and destroy them without killing or damaging healthy cells. Any other chemistry would damage and likely kill healthy cells. Our findings could play a pivotal role in providing a better, life-saving treatment option for cancer patients.”

Metastatic cancer occurs when cancer spreads to distant parts of the body, often to the bone, liver, lungs and brain, through a process called metastasis. Many types of cancers refer to this as stage IV cancer. Once cancer spreads, it can be difficult to control, and most metastatic cancer can’t be cured with current treatments, according to the National Institute of Health’s National Cancer Institute. One of the most dangerous ways metastasizing occurs is through the CTCs, which this study aims to detect and destroy using spasers. The spasers used in this study measure just 22 nanometers, setting the record for the smallest nanolasers.

The findings are published in the journal Nature Communications.

Source: http://news.gsu.edu/

AR Smart Glasses, Next Frontier Of FaceBook

Facebook is hard at work on the technical breakthroughs needed to ship futuristic smart glasses that can let you see virtual objects in the real world. A patent application for a “waveguide display with two-dimensional scanner” was published on Thursday by three members from the advanced research division of Facebook’s virtual-reality subsidiary, Oculus.

The smart glasses being developed by Oculus will use a waveguide display to project light onto the wearer’s eyes instead of a more traditional display. The smart glasses would be able to display images, video, and work with connected speakers or headphones to play audio when worn.The display “may augment views of a physical, real-world environment with computer-generated elements” and “may be included in an eye-wear comprising a frame and a display assembly that presents media to a user’s eyes,” according to the filing.

By using waveguide technology, Facebook is taking a similar approach to Microsoft‘s HoloLens AR headset and the mysterious glasses being developed by the Google-backed startup Magic Leap.

One of the authors of the patent is, in fact, lead Oculus optical scientist Pasi Saarikko, who joined Facebook in 2015 after leading the optical design of the HoloLens at Microsoft.

While work is clearly being done on the underlying technology for Facebook‘s smart glasses now, don’t expect to see the device anytime soon. Michael Abrash, the chief scientist of Oculus, recently said that AR glasses won’t start replacing smartphones until as early as 2022.

Facebook CEO Mark Zuckerberg has called virtual and augmented reality the next major computing platform capable of replacing smartphones and traditional PCs. Facebook purchased Oculus for $2 billion in 2014 and plans to spend billions more on developing the technology.

Source: http://pdfaiw.uspto.gov/
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http://www.businessinsider.com

Magnetic Fields To Remotely Control Body Movements

Scientists have used magnetism to activate tiny groups of cells in the brain, inducing bodily movements that include running, rotating and losing control of the extremities — an achievement that could lead to advances in studying and treating neurological disease. The technique researchers developed is called magneto-thermal stimulation. It gives neuroscientists a powerful new tool: a remote, minimally invasive way to trigger activity deep inside the brain, turning specific cells on and off to study how these changes affect physiology.

Magnetic nanoparticles stimulate neurons deep in the brain to evoke body movements of mice. This image shows a section of a mouse brain with injected magnetic nanoparticles (colored red) covering targeted cells in the striatum

There is a lot of work being done now to map the neuronal circuits that control behavior and emotions,” says lead researcher Arnd Pralle, PhD, a professor of physics in the University at Buffalo College of Arts and Sciences. “How is the computer of our mind working? The technique we have developed could aid this effort greatly.”

Understanding how the brain works — how different parts of the organ communicate with one another and control behavior — is key to developing therapies for diseases that involve the injury or malfunction of specific sets of neurons. Traumatic brain injuries, Parkinson’s disease, dystonia and peripheral paralysis all fall into this category.

The advances reported by Pralle’s team could also aid scientists seeking to treat ailments such as depression and epilepsy directly through brain stimulation.

Source: http://www.buffalo.edu/

Green Solar Panels And Other Colors

Researchers from AMOLF, the University of Amsterdam (UvA) and the Energy Research Centre of the Netherlands (ECN) have developed a technology to create efficient bright green colored solar panels. Arrays of silicon nanoparticles integrated in the front module glass of a silicon heterojunction solar cell scatter a narrow band of the solar spectrum and create a green appearance for a wide range of angles. The remainder of the solar spectrum is efficiently coupled into the solar cell. The current generated by the solar panel is only  reduced by 10%. The realization of efficient colorful solar panels is an important step for the integration of solar panels into the built environment and landscape.
Photovoltaic
research has much focused on maximizing the electricity yield obtained from solar panels: nowadays, commercial panels have a maximum conversion efficiency from sunlight into electricity of around 22%. To reach such high efficiency, silicon solar cells have been equipped with a textured surface with an antireflection layer to absorb as much light as possible. This creates a dark blue or black appearance of the solar panels.

To create the colored solar panels the researchers have used the effect of Mie scattering, the resonant backscattering of light with a particular color by nanoparticles. They integrated dense arrays of silicon nanocylinders with a diameter of 100 nm in the top module cover slide of a high-efficiency silicon heterojunction solar cell. Due to the resonant nature of the light scattering effect, only the green part of the spectrum is reflected; the other colors are fully coupled into the solar cell. The current generated by the mini solar panel (0,7 x 0,7 cm2)  is only reduced by 10%. The solar panel appears green over a broad range of angles up to 75 degrees. The nanoparticles are fabricated using soft-imprint lithography, a technique that can readily be scaled up to large-area fabrication.
The light scattering effect due to Mie resonances is easily controllable: by changing the size of the nanoparticles the wavelength of the resonant light scattering can be tuned. Following this principle the researchers are now working to realize solar cells in other colors, and on a combination of different colors to create solar panels with a white appearance. For the large-scale application of solar panels, it is essential that their color can be tailored.

The new design was published online in the journal Applied Physics Letters.

Source: https://amolf.nl/

Chinese Quantum Satellite Sends ‘Unbreakable’ Code

China has sent an “unbreakablecode from a satellite to the Earth, marking the first time space-to-ground quantum key distribution technology has been realized, state media said. China launched the world’s first quantum satellite last August, to help establish “hack proofcommunications, a development the Pentagon has called a “notable advance“. The official Xinhua news agency said the latest experiment was published in the journal Nature, where reviewers called it a “milestone“.

The satellite sent quantum keys to ground stations in China between 645 km (400 miles) and 1,200 km (745 miles) away at a transmission rate up to 20 orders of magnitude more efficient than an optical fiber, Xinhua cited Pan Jianwei, lead scientist on the experiment from the state-run Chinese Academy of Sciences, as saying.

That, for instance, can meet the demand of making an absolute safe phone call or transmitting a large amount of bank data,” Pan said. Any attempt to eavesdrop on the quantum channel would introduce detectable disturbances to the system, Pan said. “Once intercepted or measured, the quantum state of the key will change, and the information being intercepted will self-destruct,” Xinhua said.

The news agency said there were “enormous prospects” for applying this new generation of communications in defense and finance.

Source: http://www.reuters.com/

New WIFI Speeds Up To 300 Times Faster

Researchers at the Eindhoven University of Technology (Netherlands) say their new wireless network that uses harmless infrared rays will make wifi speeds up to 300 times faster.


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“What we are doing actually is using rays of light which convey the information in a wireless way, and each ray is acting as a very high capacity channel. It’s actually the same as an optical fibre without needing the fibre, and what we achieved up to this moment is 112 gigabits per second,” says Professor Ton Koonen, Eindhoven University of Technology.

That’s the equivalent data of three full-length movies being downloaded per second. Light antennas radiate multiple invisible wavelengths at various angles. If a user’s smartphone or tablet moves out of one antenna’s sightline, another takes over. Infrared wavelengths don’t go into your eyes, making them safe to use. The lack of moving parts makes the system maintenance and power-free. While each user gets their own antenna.

The big benefits we see of our technique is that you offer unshared capacity to each individual user, so you get a guaranteed capacity. Next to that you only get a beam if you need the traffic. So we’re not illuminating the whole place where maybe a single user is there. That means it’s much more power efficient. Another efficiency, another advantage, is that light doesn’t go through walls. So that means your communication is really confined to the particular room. Nobody can listen in from outside, so it offers you a lot of security,” explains rofessor Ton Koonen.
The team is seeking funding to help make the technology widespread within five years.

Source: http://www.reuters.com/

Biodegradable Car

TU/Ecomotive (Netherlands) says ‘Lina‘ is the world’s first car with a fully biocomposite body structure. The 4-seat e-car‘s chassis uses a combination of bio-composite and bio-plastic made from sugarbeet.

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It’s made of flax, the outside is made of flax fibres, together with polypropylene. It’s pressed and heated to make flat panels. In the middle you can see polylactic acid, the honeycomb structure of that material, which adds to the strength and weight savings of the sandwich panel. All structural parts of the car are made of this material,” says Yanic Van Riel, TU/Ecomotive.

The biocomposite has a similar strength-weight ratio to fibreglass, making the car light, greatly reducing battery size.

The car weighs only 310 kilograms which is really light for a car. That’s why we only need 30 kilograms of batteries. And on those 30 kilograms of battery packs we can drive around 100 kilometres, which is about four times more efficient than a BMW i3 right now and that’s in real city driving, so braking, stopping, accelerating, not just like the most optimal driving,” explains Yanic Van Riel.

Lina has a top speed of around 50 miles per hour. Electronic features include NFCnearfield communication technology.  “We can open our doors with NFC technology and a car will immediately recognise who is driving it. So if I’m opening it, it will save all the data from me and if someone else opens it, it will save his data. In that way we can use this car for carsharing apps, which other companies are creating. Also we have a hood system which projects the speed and all the information of the car into the front window, so we can see it through the window and still see the road, so it’s more safe,” adds Noud Van De Gevel, TU/Ecomotive.

The team hopes the prototype will soon be declared roadworthy, allowing it to be tested on Eindhoven city streets.

Source: http://tuecomotive.nl/

Pilotless Cargo Flights By 2025

Pilotless planes would save airlines $35bn (£27bn) a year and could lead to substantial fare cuts – if passengers were able to stomach the idea of remote-controlled flying, according to new research. The savings for carriers could be huge, said investment bank UBS, even though it may take until the middle of the century for passengers to have enough confidence to board a pilotless plane. UBS estimated that pilots cost the industry $31bn a year, plus another $3bn in training, and that fully automated planes would fly more efficiently, saving another $1bn a year in fuel.

Passengers could benefit from a reduction in ticket prices of about a tenth, the report said. “The average percentage of total cost and average benefit that could be passed onto passengers in price reduction for the US airlines is 11%,” it said, although the savings in Europe would be less, at 4% on average but rising to 8% at RyanairAircraft costs and fuel make up a much larger proportion of costs at airlines than pilot salaries, but UBS said profits at some major airlines could double if they switched to pilotless.

More than half of the 8,000 people UBS surveyed, however, said they would refuse to travel in a pilotless plane, even if fares were cut. “Some 54% of respondents said they were unlikely to take a pilotless flight, while only 17% said they would likely undertake a pilotless flight. Perhaps surprisingly, half of the respondents said that they would not buy the pilotless flight ticket even if it was cheaper,” the report said. It added, however, that younger and more educated respondents were more willing to fly on a pilotless plane. “This bodes well for the technology as the population ages,” it said.

Source: https://www.theguardian.com/

No More Batteries For Cellphones

University of Washington (UW) researchers have invented a cellphone that requires no batteries — a major leap forward in moving beyond chargers, cords and dying phones. Instead, the phone harvests the few microwatts of power it requires from either ambient radio signals or light.

The team also made Skype calls using its battery-free phone, demonstrating that the prototype made of commercial, off-the-shelf components can receive and transmit speech and communicate with a base station.

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We’ve built what we believe is the first functioning cellphone that consumes almost zero power,” said co-author Shyam Gollakota, an associate professor in the Paul G. Allen School of Computer Science & Engineering at the UW. “To achieve the really, really low power consumption that you need to run a phone by harvesting energy from the environment, we had to fundamentally rethink how these devices are designed.”

The team of UW computer scientists and electrical engineers eliminated a power-hungry step in most modern cellular transmissionsconverting analog signals that convey sound into digital data that a phone can understand. This process consumes so much energy that it’s been impossible to design a phone that can rely on ambient power sources. Instead, the battery-free cellphone takes advantage of tiny vibrations in a phone’s microphone or speaker that occur when a person is talking into a phone or listening to a call.

An antenna connected to those components converts that motion into changes in standard analog radio signal emitted by a cellular base station. This process essentially encodes speech patterns in reflected radio signals in a way that uses almost no power. To transmit speech, the phone uses vibrations from the device’s microphone to encode speech patterns in the reflected signals. To receive speech, it converts encoded radio signals into sound vibrations that that are picked up by the phone’s speaker. In the prototype device, the user presses a button to switch between these two “transmitting” and “listening” modes.

The new technology is detailed in a paper published July 1 in the Proceedings of the Association for Computing Machinery on Interactive, Mobile, Wearable and Ubiquitous Technologies.

Source: http://www.washington.edu/
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Brain Cells Found To Control Aging

Scientists at Albert Einstein College of Medicine have found that stem cells in the brain’s hypothalamus govern how fast aging occurs in the body. The finding, made in mice, could lead to new strategies for warding off age-related diseases and extending lifespan. The hypothalamus was known to regulate important processes including growth, development, reproduction and metabolism. In a 2013 Nature paper, Einstein researchers made the surprising finding that the hypothalamus also regulates aging throughout the body. Now, the scientists have pinpointed the cells in the hypothalamus that control aging: a tiny population of adult neural stem cells, which were known to be responsible for forming new brain neurons.

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Our research shows that the number of hypothalamic neural stem cells naturally declines over the life of the animal, and this decline accelerates aging,” says senior author Dongsheng Cai, M.D., Ph.D., professor of molecular pharmacology at Einstein. “But we also found that the effects of this loss are not irreversible. By replenishing these stem cells or the molecules they produce, it’s possible to slow and even reverse various aspects of aging throughout the body.”

The findings have been published online in Nature.

Source: http://www.einstein.yu.edu/
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How To Generate Any Cell Within The Patient’s Own Body

Researchers at The Ohio State University Wexner Medical Center and Ohio State’s College of Engineering have developed a new technology, Tissue Nanotransfection (TNT), that can generate any cell type of interest for treatment within the patient’s own body. This technology may be used to repair injured tissue or restore function of aging tissue, including organs, blood vessels and nerve cells.

By using our novel nanochip technology (nanocomputer), injured or compromised organs can be replaced. We have shown that skin is a fertile land where we can grow the elements of any organ that is declining,” said Dr. Chandan Sen, director of Ohio State’s Center for Regenerative Medicine & Cell Based Therapies, who co-led the study with L. James Lee, professor of chemical and biomolecular engineering with Ohio State’s College of Engineering in collaboration with Ohio State’s Nanoscale Science and Engineering Center.

Researchers studied mice and pigs in these experiments. In the study, researchers were able to reprogram skin cells to become vascular cells in badly injured legs that lacked blood flow. Within one week, active blood vessels appeared in the injured leg, and by the second week, the leg was saved. In lab tests, this technology was also shown to reprogram skin cells in the live body into nerve cells that were injected into brain-injured mice to help them recover from stroke.

This is difficult to imagine, but it is achievable, successfully working about 98 percent of the time. With this technology, we can convert skin cells into elements of any organ with just one touch. This process only takes less than a second and is non-invasive, and then you’re off. The chip does not stay with you, and the reprogramming of the cell starts. Our technology keeps the cells in the body under immune surveillance, so immune suppression is not necessary,” said Sen, who also is executive director of Ohio State’s Comprehensive Wound Center.

Results of the regenerative medicine study have been published in the journal  Nature Nanotechnology.

Source: https://news.osu.edu/

Hyperloop, Train Of The Future, Nearly Hits 200 mph

After announcing “the successful completion of the world’s first full systems Hyperloop test in a vacuum environment” last month, Hyperloop One is now releasing the details of a new test with their actual pod in their vacuum test tube.

They achieved a new top speed of 192 mph (310 km an hour).

Shervin Pishevar, Executive Chairman and Co-founder of Hyperloop One, made the announcement

This is the beginning, and the dawn of a new era of transportation. We’ve reached historic speeds of 310 km an hour, and we’re excited to finally show the world the XP-1 going into the Hyperloop One tube. When you hear the sound of the Hyperloop One, you hear the sound of the future.”

It’s still not on par with the ~700 mph speed that they originally planned the system to enable, but the full-scale 500-meter test track is shorter than the previously announced 1-mile long tube and it is still early in their development process.

They achieved the new top speed on just 300 meters of propulsion ramp, which is impressive, and they increased the speed by 2.7x over last month’s first test. The company disclosed that “all components of the system were successfully tested, including the highly efficient electric motor, advanced controls and power electronics, custom magnetic levitation and guidance, pod suspension and vacuum system.”

Source: https://hyperloop-one.com/
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https://electrek.co/

Male Unfertility Rises Sharply In Developed World

Male fertility in the developed world is in sharp decline. A new study from the Hebrew University of Jerusalem shows a 52.4 percent fall in sperm concentration While total sperm count fell 59.3 percent between 1973 and 2011.

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Our findings of sharp decline in sperm count among western men is the canary in the coal mine. It signifies that we have a serious problem with the health of men in the western world,” says Hagai Levine, lead-researcher at Hebrew University-Hadassah School of Public Health.

That’s because sperm count is a marker of men’s general health as well as fertility. The study analysed sperm count studies from across the world – and the trend was reflected in America, Europe, Australia and New Zealand. The next step is to investigate the causes of male infertility.
From previous research we know that exposure to man-made chemicals, especially during the critical period of the development of the male reproductive system in pre-natal life, in the early stages of pregnancy can severaly disrupt and can manifest later in life as low sperm count and problems with male fertility,” explains Hagai Levine. The study controlled for factors like age, sexual activity and the types of men, making its conclusions more reliable. “So if, for example, you have 50 studies in one country and they all show the same trend in declining sperm counts, including different counting methods in different groups of men, that makes it much more likely that it’s real” states Prof. Daniel Brison, scientific Director at the University of Manchester (Dept. of Reproductive Health).

The decline shows no sign of slowing. And the researchers say further research is urgently needed – and regulation of the environmental factors that may be contributing could be part of the solution.

Source: https://academic.oup.com/
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Faulty DNA Linked To Fatal Heart Condition Removed From Embryo

Scientists have modified human embryos to remove genetic mutations that cause heart failure in otherwise healthy young people in a landmark demonstration of the controversial procedure. It is the first time that human embryos have had their genomes edited outside China, where researchers have performed a handful of small studies to see whether the approach could prevent inherited diseases from being passed on from one generation to the next.

While none of the research so far has created babies from modified embryos, a move that would be illegal in many countries, the work represents a milestone in scientists’ efforts to master the technique and brings the prospect of human clinical trials one step closer. The work focused on an inherited form of heart disease, but scientists believe the same approach could work for other conditions caused by single gene mutations, such as cystic fibrosis and certain kinds of breast cancer.

This embryo gene correction method, if proven safe, can potentially be used to prevent transmission of genetic disease to future generations,” said Paula Amato, a fertility specialist involved in the US-Korean study at Oregon Health and Science University.

The scientists used a powerful gene editing tool called Crispr-Cas9 to fix mutations in embryos made with the sperm of a man who inherited a heart condition known as hypertrophic cardiomyopathy, or HCM. The disease, which leads to a thickening of the heart’s muscular wall, affects one in 500 people and is a common cause of sudden cardiac arrest in young people. Humans have two copies of every gene, but some diseases are caused by a mutation in only one of the copies. For the study, the scientists recruited a man who carried a single mutant copy of a gene called MYBPC3 which causes HCM.

Source: https://www.theguardian.com/

New Brain Death Pathway In Alzheimer’s Identified

Findings of team led by the Arizona State University (ASU) scientists offer hope for therapies targeting cell loss in the brain, an inevitable and devastating outcome of Alzheimer’s progression
Alzheimer’s disease tragically ravages the brains, memories and, ultimately, personalities of its victims. Now affecting 5 million Americans, Alzheimer’s disease is the sixth-leading cause of death in the U.S., and a cure for Alzheimer’s remains elusive, as the exact biological events that trigger it are still unknown.

In a new study, Arizona State University-Banner Health neuroscientist Salvatore Oddo and his colleagues from Phoenix’s Translational Genomics Research Institute (TGen) — as well as the University of California, Irvine, and Mount Sinai in New York — have identified a new way for brain cells to become fated to die during Alzheimer’s disease. The research team has found the first evidence that the activation of a biological pathway called necroptosis, which causes neuronal loss, is closely linked with Alzheimer’s severity, cognitive decline and extreme loss of tissue and brain weight that are all advanced hallmarks of the disease.

We anticipate that our findings will spur a new area of Alzheimer’s disease research focused on further detailing the role of necroptosis and developing new therapeutic strategies aimed at blocking it,” said Oddo, the lead author of this study, and scientist at the ASU-Banner Neurodegenerative Disease Research Center at the Biodesign Institute and associate professor in the School of Life Sciences.

Necroptosis, which causes cells to burst from the inside out and die, is triggered by a triad of proteins. It has been shown to play a central role in multiple sclerosis and Lou Gehrig’s disease (amyotrophic lateral sclerosis, or ALS), and now for the first time, also in Alzheimer’s disease.

There is no doubt that the brains of people with Alzheimer’s disease have fewer neurons,” explained Oddo. “The brain is much smaller and weighs less; it shrinks because neurons are dying. That has been known for 100 years, but until now, the mechanism wasn’t understood.
The findings appear in the advanced online edition of Nature Neuroscience.

Source: https://asunow.asu.edu/

By 2025 Renewables Will Power 67 Percent Of South Australia

Declining renewables and energy storage costs will increasingly squeeze out gas-fired generation in South Australia as early as 2025, a joint research report conducted by Wood Mackenzie and GTM Research shows. The South Australia experience is noteworthy in a global power mix set to increasingly shift to renewable energy. South Australia retired its last coal plant in 2016 and is projected to have installed renewable energy capacity exceed its peak demand by 2020.

By 2025, wind, solar and battery costs will fall by 15 percent, 25 percent and 50 percent respectively. By then, renewables and batteries could offer a lower cost alternative to combined-cycle gas turbine plants, which are commonly used to manage base load power generation in South Australia. Meanwhile by 2035, renewables and batteries will provide a commercial solution for both base loads and peak loads. As a consequence, gas will increasingly be used just for emergency back-up.

One determining factor is the rate with which battery charging costs declines. By 2025, we expect battery charging cost to decrease as off-peak prices will gradually be set by excess wind generation. Battery storage then becomes a potential solution for managing peak loads,” said Bikal Pokharel, principal analyst for Wood Mackenzie‘s Asia-Pacific power and renewables .
By 2025 it’s expected that 67 percent of South Australia’s power capacity will come from renewables. Gas demand in the power sector will then decline by 70 percent.

Currently, South Australia’s peak loads are managed by open-cycle gas turbine (OCGT) plants. But by 2025, battery storage would be cheaper than OCGTs in managing peak loads even at gas price of A$7/mmbtu. OCGTs would then be relegated as emergency back-ups.”

Source: https://www.woodmac.com/

Cheap, Robust Catalyst Splits Water Into Hydrogen And Oxygen

Splitting water into hydrogen and oxygen to produce clean energy can be simplified with a single catalyst developed by scientists at Rice University and the University of Houston. The electrolytic film produced at Rice and tested at Houston is a three-layer structure of nickel, graphene and a compound of iron, manganese and phosphorus. The foamy nickel gives the film a large surface, the conductive graphene protects the nickel from degrading and the metal phosphide carries out the reactionRice chemist Kenton Whitmire and Houston electrical and computer engineer Jiming Bao and their labs developed the film to overcome barriers that usually make a catalyst good for producing either oxygen or hydrogen, but not both simultaneously.

A catalyst developed by Rice University and the University of Houston splits water into hydrogen and oxygen without the need for expensive metals like platinum. This electron microscope image shows nickel foam coated with graphene and then the catalytic surface of iron, manganese and phosphorus

Regular metals sometimes oxidize during catalysis,” Whitmire said. “Normally, a hydrogen evolution reaction is done in acid and an oxygen evolution reaction is done in base. We have one material that is stable whether it’s in an acidic or basic solution.

The discovery builds upon the researchers’ creation of a simple oxygen-evolution catalyst revealed earlier this year. In that work, the team grew a catalyst directly on a semiconducting nanorod array that turned sunlight into energy for solar water splittingElectrocatalysis requires two catalysts, a cathode and an anode. When placed in water and charged, hydrogen will form at one electrode and oxygen at the other, and these gases are captured. But the process generally requires costly metals to operate as efficiently as the Rice team’s catalyst.

The standard for hydrogen evolution is platinum,” Whitmire explained. “We’re using Earth-abundant materials — iron, manganese and phosphorus — as opposed to noble metals that are much more expensive.

The robust material is the subject of a paper in Nano Energy.

Source: http://news.rice.edu/

Multi-AntiOxidant Nanoparticles Fight Sepsis

With an incidence of 31.5 million worldwide and a mortality of around 17%, sepsis remains the most common cause of death in hospitalized patients, even in industrialized countries where antibiotics and critical care facilities are readily available. While this disease begins as a serious infection, sepsis‘ life-threatening organ failure is due to an excessive inflammatory response.

By overproducing oxygen free radicals, the immunity of the host itself paradoxically leads to an increase in morbidity and mortality. A team of researchers from Center for Nanoparticle Research, within the  (IBS), with colleagues from the Seoul National University Hospital synthesized nanoparticles with superior antioxidant properties to treat sepsis in rats and mice by removing harmful oxygen radicals and reducing inflammatory responses.

Under normal physiological conditions, oxygen radicals, also called reactive oxygen species (ROS), are created as by-products of several cellular reactions and their concentration is counterbalanced by antioxidant enzymes, such as superoxide dismutase (SOD) and catalase (CAT). However in patients with severe infections, the production of ROS as well as reactive nitrogen species (RNS), increases dramatically, while the body’s antioxidant capacity may be compromised. As a consequence, the ROS and RNS accumulation can lead to damages to DNA, proteins, and lipid membranes.

All major diseases are related to ROS,” explains HYEON Taeghwan, the director of the Center for Nanoparticle Research. “Cellular damage caused by ROS has been found not only in sepsis, but also in cancer, diabetes, cardiovascular disease, atherosclerosis, and neurodegenerative diseases, just to name a few.”

Ceria nanoparticles replace the function of antioxidant enzymes. Cerium trivalent ions (Ce3+) play a decisive role in eliminating ROS. Thanks to the addition of zirconium ions, the scientists could create a new type of nanoparticles, named 7CZ (containing 70% Ce ions and 30% Zr ions), with optimized nanoparticle size and Ce3+ content. The nanoparticles described in this study are smaller, just two nanometers in size. Moreover, they have a higher percent of Ce3+. When tested in mice with sepsis, the survival rate increased 2.5 fold in the 7CZ NP-treated group compared to the control. Scientists found that 7CZ nanoparticles can infiltrate the damaged tissue and act locally at the infection site.

Treating sepsis has been an old challenge for physicians worldwide,” emphasizes LEE Seung-Hoon, professor of department of Neurology, Seoul National University Hospital. “This study shows the possibility of overcoming the limits of modern medicine with nanotechnology.”

This study has been published in the journal Angewandte Chemie.

Source: ,http://www.ibs.re.kr/

New Solar System Produces 50 Percent More Energy

A concentrating photovoltaic system (CPV) with embedded microtracking can produce over 50 percent more energy per day than standard silicon solar cells in a head-to-head competition, according to a team of engineers who field tested a prototype unit over two sunny days last fall.

Solar cells used to be expensive, but now they’re getting really cheap,” said Chris Giebink, Charles K. Etner Assistant Professor of Electrical Engineering, Penn State. “As a result, the solar cell is no longer the dominant cost of the energy it produces. The majority of the cost increasingly lies in everything else — the inverter, installation labor, permitting fees, etc. — all the stuff we used to neglect.

This changing economic landscape has put a premium on high efficiency. In contrast to silicon solar panels, which currently dominate the market at 15 to 20 percent efficiency, concentrating photovoltaics focus sunlight onto smaller, but much more efficient solar cells like those used on satellites, to enable overall efficiencies of 35 to 40 percent. Current CPV systems are large — the size of billboards — and have to rotate to track the sun during the day. These systems work well in open fields with abundant space and lots of direct sun.

What we’re trying to do is create a high-efficiency CPV system in the form factor of a traditional silicon solar panel,” said Giebink.

Source: http://news.psu.edu/

Clothes Embedded With Nanoparticles Heal The Skin

Tiny capsules embedded in the clothes we wear could soon be used to counteract the rise of sensitive skin conditions.

As people are getting older, they have more sensitive skin, so there is a need to develop new products for skin treatment,” says Dr Carla Silva, from the Centre for Nanotechnology and Smart Materials (CENTI), in Portugal

This increased sensitivity can lead to painful bacterial infections such as dermatitis, otherwise known as eczema. Current treatments use silver-based or synthetic antibacterial elements, but these can create environmentally harmful waste and may have negative side effects.

To combat these bacterial infections in an eco-friendly way the EU-funded SKHINCAPS project is combining concentrated plant oil with nanotechnology. Their solution puts these so-called essential oils into tiny capsules that are hundreds of times smaller than the width of a human hair. Each one is programmed to release its payload only in the presence of the bacteria that cause the skin infections. This means that each capsule is in direct contact with the affected skin as soon as an infection occurs, increasing the effectiveness of the treatment.

According to Dr Silva, who is also project coordinator of SKHINCAPS, the nano-capsules are attached to the clothing material using covalent bonding, the strongest chemical bond found in nature. This ensures the capsules survive the washing machine and that they are invisible to whoever is wearing them. This nanotechnology has a lifespan equal to that of the garment, though the active ingredients contained in the nano-capsules will run out earlier depending on the extent of the skin infection, and thereby on how much of the treatment is released when the clothing is worn.

The nano-capsules will prove invaluable for chronic eczema sufferers and those with high levels of stress, as well as the elderly and diabetics, who are particularly vulnerable to developing such infections.

Source: https://horizon-magazine.eu/

Move And Produce Electricity To Power Your Phone

Imagine slipping into a jacket, shirt or skirt that powers your cell phone, fitness tracker and other personal electronic devices as you walk, wave and even when you are sitting down. A new, ultrathin energy harvesting system developed at Vanderbilt University’s Nanomaterials and Energy Devices Laboratory has the potential to do just that. Based on battery technology and made from layers of black phosphorus that are only a few atoms thick, the new device generates small amounts of electricity when it is bent or pressed even at the extremely low frequencies characteristic of human motion.

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In the future, I expect that we will all become charging depots for our personal devices by pulling energy directly from our motions and the environment,” said Assistant Professor of Mechanical Engineering Cary Pint, who directed the research.
This is timely and exciting research given the growth of wearable devices such as exoskeletons and smart clothing, which could potentially benefit from Dr. Pint’s advances in materials and energy harvesting,” observed Karl Zelik, assistant professor of mechanical and biomedical engineering at Vanderbilt, an expert on the biomechanics of locomotion who did not participate in the device’s development.

Doctoral students Nitin Muralidharan and Mengya Lic o-led the effort to make and test the devices. When you look at Usain Bolt, you see the fastest man on Earth. When I look at him, I see a machine working at 5 Hertz, said Muralidharan.

The new energy harvesting system is described in a paper titled “Ultralow Frequency Electrochemical Mechanical Strain Energy Harvester using 2D Black Phosphorus Nanosheets” published  by the journal ACS Energy Letters.

Source: https://news.vanderbilt.edu/

SuperPowerful Tiny Device Converts Light Into Electricity

In today’s increasingly powerful electronics, tiny materials are a must as manufacturers seek to increase performance without adding bulk. Smaller also is better for optoelectronic devices — like camera sensors or solar cells —which collect light and convert it to electrical energy. Think, for example, about reducing the size and weight of a series of solar panels, producing a higher-quality photo in low lighting conditions, or even transmitting data more quickly.

However, two major challenges have stood in the way: First, shrinking the size of conventionally used “amorphousthin-film materials also reduces their quality. And second, when ultrathin materials become too thin, they are almost transparent — and actually lose some ability to gather or absorb light.

Now, in a nanoscale photodetector that combines both a unique fabrication method and light-trapping structures, a team of engineers from the University at Buffalo (UB) and the University of Wisconsin-Madison (UW-Madison) has overcome both of those obstacles. The researchers — electrical engineers Qiaoqiang Gan at UB, and Zhenqiang (Jack) Ma and Zongfu Yu at UW-Madison — described their device, a single-crystalline germanium nanomembrane photodetector on a nanocavity substrate, in the July 7, 2017, issue of the journal Science Advances.

This image shows the different layers of the nanoscale photodetector, including germanium (red) in between layers of gold or aluminum (yellow) and aluminum oxide (purple). The bottom layer is a silver substrate

We’ve created an exceptionally small and extraordinarily powerful device that converts light into energy,” says Gan, associate professor of electrical engineering in UB’s School of Engineering and Applied Sciences, and one of the paper’s lead authors. “The potential applications are exciting because it could be used to produce everything from more efficient solar panels to more powerful optical fibers.”

The idea, basically, is you want to use a very thin material to realize the same function of devices in which you need to use a very thick material,” says Ma, the Lynn H. Matthias Professor and Vilas Distinguished Achievement Professor in electrical and computer engineering at UW-Madison, also a lead author. Nanocavities are made up of an orderly series of tiny, interconnected molecules that essentially reflect, or circulate, light.

The new device is an advancement of Gan’s work developing nanocavities that increase the amount of light that thin semiconducting materials like germanium can absorb. It consists of nanocavities sandwiched between a top layer of ultrathin single-crystal germanium and a bottom, reflecting layer of silver.

Source: https://www.buffalo.edu/

How To Strengthen 3-D Printed Parts

From aerospace and defense to digital dentistry and medical devices, 3-D printed parts are used in a variety of industries. Currently, 3-D printed parts are very fragile and traditionally used in the prototyping phase of materials or as a toy for display. A doctoral student in the Department of Materials Science and Engineering at Texas A&M University has pioneered a countermeasure to transform the landscape of 3-D printing today.

Brandon Sweeney and his advisor Dr. Micah Green, associate professor in the Department of Chemical Engineering, discovered a way to make 3-D printed parts stronger and immediately useful in real-world applications. Sweeney and Green applied the traditional welding concepts to bond the submillimeter layers in a 3-D printed part together, while in a microwave.

I was able to see the amazing potential of the technology, such as the way it sped up our manufacturing times and enabled our CAD designs to come to life in a matter of hours,” Sweeney said. “Unfortunately, we always knew those parts were not really strong enough to survive in a real-world application.

3-D printed objects are comprised of many thin layers of materials, plastics in this case, deposited on top of each other to form a desired shape. These layers are prone to fracturing, causing issues with the durability and reliability of the part when used in a real-world application, for example a custom printed medical device. “I knew that nearly the entire industry was facing this problem,” Sweeney said. “Currently, prototype parts can be 3-D printed to see if something will fit in a certain design, but they cannot actually be used for a purpose beyond that.”

When Sweeney started his doctorate, he was working with Green in the Department of Chemical Engineering at Texas Tech University. Green had been collaborating with Dr. Mohammad Saed, assistant professor in the electrical and computer engineering department at Texas Tech, on a project to detect carbon nanotubes using microwaves. The trio crafted an idea to use carbon nanotubes in 3-D printed parts, coupled with microwave energy to weld the layers of parts together.

The basic idea is that a 3-D part cannot simply be stuck into an oven to weld it together because it is plastic and will melt,” Sweeney said. “We realized that we needed to borrow from the concepts that are traditionally used for welding parts together where you’d use a point source of heat, like a torch or a TIG welder to join the interface of the parts together. You’re not melting the entire part, just putting the heat where you need it.” The technology is patent-pending and licensed with a local company, Essentium Materials.

The team recently published a paper “Welding of 3-D Printed Carbon Nanotube-Polymer Composites by Locally Induced Microwave Heating,” in Science Advances.

Source: http://engineering.tamu.edu/

Hydrogen-based Electric Bus

FAST, a student team from Eindhoven University of Technology (TU/e) in Netherlands, has designed the world’s first system that allows a bus to drive on formic acid. Their self-built system comprises an electric bus that is hooked up to a small trailer – which the students have christened ‘REX’ – in which formic acid is converted into electricity. The benefits of using formic acid are that it is sustainable, CO2-neutral, safe and liquid.

 

Hydrozine is the energy carrier’s official name. It’s 99% formic acid with a performance enhancing agent. What is striking is that Team FAST, consisting of 35 students, developed this so far unknown fuel all by itself. At the beginning of 2016 they presented an initial scale model that illustrated how it works. After another twenty months of hard work, they now have a system that is 42,000 times stronger and is capable of 25kW power.

In the trailer that was built by the team hydrozine is split into hydrogen and CO2. The hydrogen is then used to produce electricity that powers a city bus of the Eindhoven company VDL. The team calls the trailer a ‘range extender’, REX for short, because the trailer expands the existing range of the bus as a standalone component. The team is still running final tests with the aim of the bus actually operating by the end of this year.

The benefits of hydrozine are many. It is a cheap and safe alternative to the transport of hydrogen that normally requires large tanks and high pressure. The CO2 produced in splitting the hydrozine is also used in the production process, which results in zero net CO2. Hydrozine has four times as much energy density as a battery and since it is a liquid, very few modifications will be required to the current infrastructure of filling stations.

Source: https://www.tue.nl/

How To Power The U.S. With Solar

Speaking recently at the National Governors Association Summer Meeting in Rhode Island, Elon Musk told his audience — including 30 United States governors — that it’s possible to power the nation with solar energy.

If you wanted to power the entire U.S. with solar panels, it would take a fairly small corner of Nevada or Texas or Utah; you only need about 100 miles by 100 miles of solar panels to power the entire United States,” Musk said. “The batteries you need to store the energy, to make sure you have 24/7 power, is 1 mile by 1 mile. One square-mile. That’s it.”

Why solar? Well, as Musk explained, as far as energy sources go, we can count on solar to come through for us: “People talk about fusion and all that, but the sun is a giant fusion reactor in the sky. It’s really reliable. It comes up every day. If it doesn’t we’ve got bigger problems.”

At present, about 10 percent of the U.S. is powered by renewable energy sources. To achieve a complete renewable energy power, Musk thinks solar is the way to go.

To start, he suggested combining rooftop solar and utility-scale solar plants. The former would be on the rooftops of houses in the suburbs, while the latter could power other areas. As we’ve seen with Tesla’s new rooftop solar unit, and efforts in other countries, like Australia, to build large-scale solar plants, this is a goal well within reach.

Next, while in transition from fossil fuel to solar, it’d be necessary to rely on other renewables. “We’ll need to be a combination of utility-scale solar and rooftop solar, combined with wind, geothermal, hydro, probably some nuclear for a while, in order to transition to a sustainable situation,” Musk explained.

Finally, the U.S. has to build more localized power sources, like the rooftop solar setups. “People do not like transmission lines going through their neighborhood, they really don’t like that, and I agree,” Musk said. “Rooftop solar, utility solar; that’s really going to be a solution from the physics standpoint. I can really see another way to really do it.”

When this happens, the U.S. would eliminate about 1,821 million metric tons of carbon dioxide (CO2) emissions generated by the country’s current electric power sector — 35 percent of the overall CO2 energy-related emissions in the U.S.

Source: https://futurism.com/

Solar Nanotechnology-based Desalination

A new desalination system has been developed that combines membrane distillation technology and light-harvesting nanophotonics. Called nanophotonics-enabled solar membrane distillation technology, or NESMD for short, the development has come from the Center for Nanotechnology Enabled Water Treatment (NEWT), based at Rice University. The system works whereby hot salt water is flowed across one side of a porous membrane and cold freshwater is flowed across the otherWater vapor is naturally drawn through the membrane from the hot to the cold side, and because the seawater doesn’t need to be boiled, the energy requirements are less than they would be for traditional distillation, according to the researchers. However, the energy costs are still significant because heat is continuously lost from the hot side of the membrane to the cold.

Unlike traditional membrane distillation, NESMD benefits from increasing efficiency with scale,” said Rice’s Naomi Halas, a corresponding author on the paper and the leader of NEWT‘s  nanophotonics research efforts. “It requires minimal pumping energy for optimal distillate conversion, and there are a number of ways we can further optimise the technology to make it more productive and efficient.

The distillation membrane in the chamber contained a specially designed top layer of carbon black nanoparticles infused into a porous polymer. The light-capturing nanoparticles heated the entire surface of the membrane when exposed to sunlight. A thin half-millimeter-thick layer of salt water flowed atop the carbon-black layer, and a cool freshwater stream flowed below.

Rice scientist and water treatment expert Qilin Li said the water production rate increased greatly by concentrating the sunlight: “The intensity got up 17.5 kilowatts per meter squared when a lens was used to concentrate sunlight by 25 times, and the water production increased to about 6 liters per meter squared per hour.”

In the PNAS study, researchers offered proof-of-concept results based on tests with an NESMD chamber about the size of three postage stamps and just a few millimeters thick.

Source: http://www.waterworld.com/

Sion, The Solar-Powered Car

What has room for 6 passengers, an all-electric range of up to 155 miles (250 kilometers), and a body covered in solar panels that can add as many as 18 miles (30 kilometers) of driving a day from sunlight? That would be the Sono Motors Sion, an innovative solar-powered car from a team of German entrepreneurs that is scheduled to have its world debut on July 27 (2017).

The Sion project was able to move forward thanks to an Indiegogo crowdfunding campaign last year that raised over a half million dollars. More than 1,000 people have participated so far.

The car will have two versions. The Urban comes with a 14.4 kilowatt-hour battery pack. It has a range of about 75 miles (121 kilometers) and will cost $13,200. The Extender version has a 30 kilowatt-hour battery and a range of 155 miles (250 kilometers). Its target price is $17,600. Neither price includes the battery. Like the Renault Zoe, customers will either buy the battery separately or lease it. The leasing option gives owners the flexibility to upgrade the battery later as improvements in battery technology become available.

The hood, roof, and rear hatch of the Sion are covered with monocrystalline silicon cells that are 21% efficient. On a sunny day, they can generate enough electricity to add 18 miles of range. The solar cells are 8 millimeters thick and embedded in a polycarbonate layer that is shatterproof, weather resistant, and light in weight. The Sion can also be 80% charged using an AC outlet in about 30 minutes, according to company claims. No DC charging option is available. The car also comes with an outlet that can power electronic devices.

Inside, all the seats of the 5 door hatchback fold flat, offering multiple configurations for carrying passengers and cargo. There is a 10 inch center display and smartphone connectivity via WiFi or Bluetooth. The ventilation system is called breSono and incorporates a dollop of moss, which is said to act as a natural filter when an electrical charge is applied.

The company will offer an online maintenance and repair system it calls reSono. It allows owners to order parts online and comes with a video that shows them how to install the parts when they arrive.  Or they can take the car and the parts to any local auto repair shop facility to get them installed.

Source: https://www.sonomotors.com/
AND
https://cleantechnica.com/

Cancer: A Giant Step For Immunotherapy

A Food and Drug Administration (FDA) panel opened a new era in medicine, unanimously recommending that the agency approve the first-ever treatment that genetically alters a patient’s own cells to fight cancer, transforming them into what scientists call “a living drug” that powerfully bolsters the immune system to shut down the disease.

If the F.D.A. accepts the recommendation, which is likely, the treatment will be the first gene therapy ever to reach the market. Others are expected: Researchers and drug companies have been engaged in intense competition for decades to reach this milestone. Novartis is now poised to be the first. Its treatment is for a type of leukemia, and it is working on similar types of treatments in hundreds of patients for another form of the disease, as well as multiple myeloma and an aggressive brain tumor.

To use the technique, a separate treatment must be created for each patient — their cells removed at an approved medical center, frozen, shipped to a Novartis plant for thawing and processing, frozen again and shipped back to the treatment center.

A single dose of the resulting product has brought long remissions, and possibly cures, to scores of patients in studies who were facing death because every other treatment had failed. The panel recommended approving the treatment for B-cell acute lymphoblastic leukemia that has resisted treatment, or relapsed, in children and young adults aged 3 to 25.

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We believe that when this treatment is approved it will save thousands of children’s lives around the world,” Emily’s father, Tom Whitehead, told the panel. “I hope that someday all of you on the advisory committee can tell your families for generations that you were part of the process that ended the use of toxic treatments like chemotherapy and radiation as standard treatment, and turned blood cancers into a treatable disease that even after relapse most people survive.”

The main evidence that Novartis presented to the F.D.A. came from a study of 63 patients who received the treatment from April 2015 to August 2016. Fifty-two of them, or 82.5 percent, went into remission — a high rate for such a severe disease. Eleven others died.

It’s a new world, an exciting therapy,” said Dr. Gwen Nichols, the chief medical officer of the Leukemia and Lymphoma Society, which paid for some of the research that led to the treatment. The next step, she said, will be to determine “what we can combine it with and is there a way to use it in the future to treat patients with less disease, so that the immune system is in better shape and real