Researchers have Combined physics and neurobiology to tackle Parkinson’s Disease. Professor Keshav Dani from the Okinawa Institute of Science and Technology (OIST) – Japan – Graduate University’s Femtosecond Spectroscopy Unit and Neurobiology Research Unit, along with collaborators at the University of Otago, New Zealand are using lasers, nanotechnology and neuroscience to develop a new, versatile drug delivery system. In a new article in Scientific Reports, the researchers describe their work using a laser to release a neurochemical, the function of which is impaired in Parkinson’s Disease, in a controlled and repeatable manner.
Currently, we administer drugs in a systemic way and tissues or organs that do not need the drug receive it, leading to unwanted side effects. A good example of this is in chemotherapy, which is toxic not only to the intended target cancer cells, but also to healthy tissue
An exciting new area of research for a cure or therapy for many diseases is targeted drug delivery. Recent advances in nanotechnology and biology are opening up the possibilities in targeted drug delivery, where researchers can release drugs or compounds in a specific tissue or even individual cells, which would allow the drug to reach only its intended target. In their recent paper, OIST researchers describe a method to encapsulate a drug in a shell of lipids, or fat, called a liposome, and modulate the release of the drug using a pulse from a laser.